Emerging Antitumor Activities of the Bitter Melon (Momordica charantia)

Evandro Fei Fang, Lynn Froetscher, Morten Scheibye-Knudsen, Vilhelm A Bohr, Jack Ho Wong, Tzi Bun Ng

5 Citationer (Scopus)

Abstract

Bitter melon or bitter gourd (Momordica charantia) is a common vegetable in Asia and it is distinctive for its bitter taste. As an ingredient in folk medicine, research from different laboratories in recent years supports its potential medicinal applications with anti-tumor, anti-diabetic, anti-HIV activities in both in vitro and animal studies. In this short review, we summarize herein the recent progress in the antitumor aspect of bitter melon with a focus on the underlying molecular mechanisms. Further mechanistic studies as well as clinical trials are necessary to further verify its medicinal applications.

OriginalsprogEngelsk
TidsskriftCurrent Protein and Peptide Science
Vol/bind20
Udgave nummer3
Sider (fra-til)296-301
Antal sider6
ISSN1389-2037
DOI
StatusUdgivet - 2019
Udgivet eksterntJa

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