Effects of endotoxaemia on markers of permeability, metabolism and inflammation in the large bowel of healthy subjects

TY - JOUR

T1 - Effects of endotoxaemia on markers of permeability, metabolism and inflammation in the large bowel of healthy subjects

AU - Jørgensen, Vibeke Renée Lind

AU - Ibsen, M.

AU - Andresen, L.

AU - Schulzke, J.D.

AU - Perner, Anders

PY - 2007

Y1 - 2007

N2 - Increased permeability and increased luminal concentrations of L-lactate have previously been shown in the large bowel in septic patients. To advance these observations, a human model of colorectal barrier failure in sepsis is desirable. Therefore, we assessed the effects of endotoxaemia on markers of permeability, metabolism and inflammation in the large bowel in healthy subjects.

AB - Increased permeability and increased luminal concentrations of L-lactate have previously been shown in the large bowel in septic patients. To advance these observations, a human model of colorectal barrier failure in sepsis is desirable. Therefore, we assessed the effects of endotoxaemia on markers of permeability, metabolism and inflammation in the large bowel in healthy subjects.

U2 - 10.1111/j.1399-6576.2007.01381.x

DO - 10.1111/j.1399-6576.2007.01381.x

M3 - Journal article

SN - 0001-5172

VL - 51

SP - 1085

EP - 1092

JO - Acta Anaesthesiologica Scandinavica

JF - Acta Anaesthesiologica Scandinavica

IS - 8

ER -