TY - JOUR
T1 - Effect of silver nanoparticles on growth performance, metabolism and microbial profile of broiler chickens
AU - Pineda, Lane Manalili
AU - Chwalibog, André
AU - Sawosz, Ewa
AU - Lauridsen, Charlotte
AU - Engberg, Ricarda Greuel
AU - Elnif, Jan
AU - Hotowy, Anna Malgorzata
AU - Sawosz, Filip
AU - Gao, Yuhong
AU - Ali, Abdalla Said Ahmed
AU - Moghaddam, Heshmat Sepehri
PY - 2012/10
Y1 - 2012/10
N2 - This study evaluated the potential of silver nanoparticles (AgNano) as an antimicrobial growth-promoting supplement for broiler chickens. One hundred forty-four seven-day-old broiler chicks were distributed randomly to AgNano treatments at 0, 10 and 20 mg/kg (Control, Group AgNano10, and Group AgNano20, respectively) provided via the drinking water from day 7 to 36 post-hatching. Body weight and feed consumption were measured weekly. In addition, balance and respiration experiments were carried out to determine nitrogen (N) utilisation and energy retention. At days 22 and 36, blood samples and intestinal content were collected to evaluate the effects of AgNano on plasma concentration of immunoglobulins and the intestinal microflora, repectively. The provision of water solutions containing different concentrations of AgNano had no effect on postnatal growth performance and the energy metabolism of broiler chickens. However, in Group AgNano10 N intake (p = 0.05) and retention (p = 0.03) was increased, but N excretion and efficiency of utilisation was not affected. The populations of bacteria in the intestinal samples were not affected by AgNano supplementation. The concentration of immunoglobulin (IgG) in the blood plasma of broilers supplemented with AgNano decreased at day 36 (p = 0.012). The results demonstrated that AgNano affects N utilisation and plasma IgG concentration; however, it does not influence the microbial populations in the digestive tract, the energy metabolism and growth performance of chickens.
AB - This study evaluated the potential of silver nanoparticles (AgNano) as an antimicrobial growth-promoting supplement for broiler chickens. One hundred forty-four seven-day-old broiler chicks were distributed randomly to AgNano treatments at 0, 10 and 20 mg/kg (Control, Group AgNano10, and Group AgNano20, respectively) provided via the drinking water from day 7 to 36 post-hatching. Body weight and feed consumption were measured weekly. In addition, balance and respiration experiments were carried out to determine nitrogen (N) utilisation and energy retention. At days 22 and 36, blood samples and intestinal content were collected to evaluate the effects of AgNano on plasma concentration of immunoglobulins and the intestinal microflora, repectively. The provision of water solutions containing different concentrations of AgNano had no effect on postnatal growth performance and the energy metabolism of broiler chickens. However, in Group AgNano10 N intake (p = 0.05) and retention (p = 0.03) was increased, but N excretion and efficiency of utilisation was not affected. The populations of bacteria in the intestinal samples were not affected by AgNano supplementation. The concentration of immunoglobulin (IgG) in the blood plasma of broilers supplemented with AgNano decreased at day 36 (p = 0.012). The results demonstrated that AgNano affects N utilisation and plasma IgG concentration; however, it does not influence the microbial populations in the digestive tract, the energy metabolism and growth performance of chickens.
KW - Animal Feed
KW - Animal Nutritional Physiological Phenomena
KW - Animals
KW - Anti-Bacterial Agents
KW - Chickens
KW - Diet
KW - Dietary Supplements
KW - Energy Metabolism
KW - Metal Nanoparticles
KW - Nitrogen
KW - Poultry Diseases
KW - Silver
KW - Water
U2 - 10.1080/1745039x.2012.710081
DO - 10.1080/1745039x.2012.710081
M3 - Journal article
C2 - 22889095
SN - 1745-039X
VL - 66
SP - 416
EP - 429
JO - Archives of Animal Nutrition
JF - Archives of Animal Nutrition
IS - 5
ER -