ECMM CandiReg—A ready to use platform for outbreaks and epidemiological studies

on behalf of the European Confederation of Medical Mycology (ECMM)

doi:10.1111/myc.12963

ECMM CandiReg—A ready to use platform for outbreaks and epidemiological studies

on behalf of the European Confederation of Medical Mycology (ECMM)

Institut for Klinisk Medicin

4 Citationer (Scopus)

Abstract

Background: Recent outbreaks of Candida auris further exemplify that invasive Candida infections are a substantial threat to patients and healthcare systems. Even short treatment delays are associated with higher mortality rates. Epidemiological shifts towards more resistant Candida spp. require careful surveillance. Objectives: Triggered by the emergence of C auris and by increasing antifungal resistance rates the European Confederation of Medical Mycology developed an international Candida Registry (FungiScope™ CandiReg) to allow contemporary multinational surveillance. Methods: CandiReg serves as platform for international cooperation to enhance research regarding invasive Candida infections. CandiReg uses the General Data Protection Regulation compliant data platform ClinicalSurveys.net that holds the electronic case report forms (eCRF). Data entry is supported via an interactive macro created by the software that can be accessed via any Internet browser. Results: CandiReg provides an eCRF for invasive Candida infections that can be used for a variety of studies from cohort studies on attributable mortality to evaluations of guideline adherence, offering to the investigators of the 28 ECMM member countries the opportunity to document their cases of invasive Candida infection. CandiReg allows the monitoring of epidemiology of invasive Candida infections, including monitoring of multinational outbreaks. Here, we describe the structure and management of the CandiReg platform. Conclusion: CandiReg supports the collection of clinical information and isolates to improve the knowledge on epidemiology and eventually to improve management of invasive Candida infections. CandiReg promotes international collaboration, improving the availability and quality of evidence on invasive Candida infection and contributes to improved patient management.

Originalsprog	Engelsk
Tidsskrift	Mycoses
ISSN	0933-7407
DOI	https://doi.org/10.1111/myc.12963
Status	Udgivet - 1 okt. 2019

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10.1111/myc.12963

Citationsformater

@article{73c61efb93f64ba1bff947e21ea9d98e,

title = "ECMM CandiReg—A ready to use platform for outbreaks and epidemiological studies",

abstract = "Background: Recent outbreaks of Candida auris further exemplify that invasive Candida infections are a substantial threat to patients and healthcare systems. Even short treatment delays are associated with higher mortality rates. Epidemiological shifts towards more resistant Candida spp. require careful surveillance. Objectives: Triggered by the emergence of C auris and by increasing antifungal resistance rates the European Confederation of Medical Mycology developed an international Candida Registry (FungiScope{\texttrademark} CandiReg) to allow contemporary multinational surveillance. Methods: CandiReg serves as platform for international cooperation to enhance research regarding invasive Candida infections. CandiReg uses the General Data Protection Regulation compliant data platform ClinicalSurveys.net that holds the electronic case report forms (eCRF). Data entry is supported via an interactive macro created by the software that can be accessed via any Internet browser. Results: CandiReg provides an eCRF for invasive Candida infections that can be used for a variety of studies from cohort studies on attributable mortality to evaluations of guideline adherence, offering to the investigators of the 28 ECMM member countries the opportunity to document their cases of invasive Candida infection. CandiReg allows the monitoring of epidemiology of invasive Candida infections, including monitoring of multinational outbreaks. Here, we describe the structure and management of the CandiReg platform. Conclusion: CandiReg supports the collection of clinical information and isolates to improve the knowledge on epidemiology and eventually to improve management of invasive Candida infections. CandiReg promotes international collaboration, improving the availability and quality of evidence on invasive Candida infection and contributes to improved patient management.",

keywords = "Candidemia, epidemiology, invasive candidiasis, invasive fungal infection, outbreak",

author = "Philipp Koehler and Arendrup, {Maiken Cavling} and Sevtap Arikan-Akdagli and Matteo Bassetti and St{\'e}phane Bretagne and Lena Klingspor and Katrien Lagrou and Meis, {Jacques F.} and Riina Rautemaa-Richardson and Silke Schelenz and Axel Hamprecht and Koehler, {Felix C.} and Oliver Kurzai and Jon Salmanton-Garc{\'i}a and Vehreschild, {J{\"o}rg Janne} and Alexandre Alanio and Ana Alastruey-Izquierdo and {Arsic Arsenijevic}, Valentina and Gangneux, {Jean Pierre} and Gow, {Neil A.R.} and Suzana Hadina and Petr Hamal and Elizabeth Johnson and Nikolay Klimko and Cornelia Lass-Fl{\"o}rl and Mihai Mares and Volkan {\"O}zenci and Tamas Papp and Emmanuel Roilides and Raquel Sabino and Esther Segal and Talento, {Alida Fe} and Tortorano, {Anna Maria} and Verweij, {Paul E.} and Martin Hoenigl and Cornely, {Oliver A.} and {on behalf of the European Confederation of Medical Mycology (ECMM)}",

year = "2019",

month = oct,

day = "1",

doi = "10.1111/myc.12963",

language = "English",

journal = "Mycoses",

issn = "0933-7407",

publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - ECMM CandiReg—A ready to use platform for outbreaks and epidemiological studies

AU - Koehler, Philipp

AU - Arendrup, Maiken Cavling

AU - Arikan-Akdagli, Sevtap

AU - Bassetti, Matteo

AU - Bretagne, Stéphane

AU - Klingspor, Lena

AU - Lagrou, Katrien

AU - Meis, Jacques F.

AU - Rautemaa-Richardson, Riina

AU - Schelenz, Silke

AU - Hamprecht, Axel

AU - Koehler, Felix C.

AU - Kurzai, Oliver

AU - Salmanton-García, Jon

AU - Vehreschild, Jörg Janne

AU - Alanio, Alexandre

AU - Alastruey-Izquierdo, Ana

AU - Arsic Arsenijevic, Valentina

AU - Gangneux, Jean Pierre

AU - Gow, Neil A.R.

AU - Hadina, Suzana

AU - Hamal, Petr

AU - Johnson, Elizabeth

AU - Klimko, Nikolay

AU - Lass-Flörl, Cornelia

AU - Mares, Mihai

AU - Özenci, Volkan

AU - Papp, Tamas

AU - Roilides, Emmanuel

AU - Sabino, Raquel

AU - Segal, Esther

AU - Talento, Alida Fe

AU - Tortorano, Anna Maria

AU - Verweij, Paul E.

AU - Hoenigl, Martin

AU - Cornely, Oliver A.

AU - on behalf of the European Confederation of Medical Mycology (ECMM)

PY - 2019/10/1

Y1 - 2019/10/1

N2 - Background: Recent outbreaks of Candida auris further exemplify that invasive Candida infections are a substantial threat to patients and healthcare systems. Even short treatment delays are associated with higher mortality rates. Epidemiological shifts towards more resistant Candida spp. require careful surveillance. Objectives: Triggered by the emergence of C auris and by increasing antifungal resistance rates the European Confederation of Medical Mycology developed an international Candida Registry (FungiScope™ CandiReg) to allow contemporary multinational surveillance. Methods: CandiReg serves as platform for international cooperation to enhance research regarding invasive Candida infections. CandiReg uses the General Data Protection Regulation compliant data platform ClinicalSurveys.net that holds the electronic case report forms (eCRF). Data entry is supported via an interactive macro created by the software that can be accessed via any Internet browser. Results: CandiReg provides an eCRF for invasive Candida infections that can be used for a variety of studies from cohort studies on attributable mortality to evaluations of guideline adherence, offering to the investigators of the 28 ECMM member countries the opportunity to document their cases of invasive Candida infection. CandiReg allows the monitoring of epidemiology of invasive Candida infections, including monitoring of multinational outbreaks. Here, we describe the structure and management of the CandiReg platform. Conclusion: CandiReg supports the collection of clinical information and isolates to improve the knowledge on epidemiology and eventually to improve management of invasive Candida infections. CandiReg promotes international collaboration, improving the availability and quality of evidence on invasive Candida infection and contributes to improved patient management.

AB - Background: Recent outbreaks of Candida auris further exemplify that invasive Candida infections are a substantial threat to patients and healthcare systems. Even short treatment delays are associated with higher mortality rates. Epidemiological shifts towards more resistant Candida spp. require careful surveillance. Objectives: Triggered by the emergence of C auris and by increasing antifungal resistance rates the European Confederation of Medical Mycology developed an international Candida Registry (FungiScope™ CandiReg) to allow contemporary multinational surveillance. Methods: CandiReg serves as platform for international cooperation to enhance research regarding invasive Candida infections. CandiReg uses the General Data Protection Regulation compliant data platform ClinicalSurveys.net that holds the electronic case report forms (eCRF). Data entry is supported via an interactive macro created by the software that can be accessed via any Internet browser. Results: CandiReg provides an eCRF for invasive Candida infections that can be used for a variety of studies from cohort studies on attributable mortality to evaluations of guideline adherence, offering to the investigators of the 28 ECMM member countries the opportunity to document their cases of invasive Candida infection. CandiReg allows the monitoring of epidemiology of invasive Candida infections, including monitoring of multinational outbreaks. Here, we describe the structure and management of the CandiReg platform. Conclusion: CandiReg supports the collection of clinical information and isolates to improve the knowledge on epidemiology and eventually to improve management of invasive Candida infections. CandiReg promotes international collaboration, improving the availability and quality of evidence on invasive Candida infection and contributes to improved patient management.

KW - Candidemia

KW - epidemiology

KW - invasive candidiasis

KW - invasive fungal infection

KW - outbreak

U2 - 10.1111/myc.12963

DO - 10.1111/myc.12963

M3 - Journal article

C2 - 31271702

AN - SCOPUS:85070057545

SN - 0933-7407

JO - Mycoses

JF - Mycoses

ER -

ECMM CandiReg—A ready to use platform for outbreaks and epidemiological studies

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