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Dynamics of urokinase receptor interaction with Peptide antagonists studied by amide hydrogen exchange and mass spectrometry
Thomas J D Jørgensen
,
Henrik Gårdsvoll
, Keld Danø, Peter Roepstorff,
Michael Ploug
Institut for Klinisk Medicin
43
Citationer (Scopus)
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Medicin og biovidenskab
Urokinase Plasminogen Activator Receptors
100%
Amides
84%
Hydrogen
82%
Urokinase-Type Plasminogen Activator
81%
Mass Spectrometry
64%
Peptides
45%
beta-cyclohexylalanyl-phenylalanyl-seryl-arginyl-tyrosyl-leucyl-tryptophyl-serine
20%
Isotopes
19%
Ligands
18%
Intercellular Signaling Peptides and Proteins
14%
Kinetics
12%
Electrospray Ionization Mass Spectrometry
12%
Fucose
11%
Peptide Receptors
11%
Hydrogen Bonding
10%
Serine Proteases
10%
Neoplasms
2%
Kemiske forbindelser
Antagonist
66%
Amide
50%
Mass Spectrometry
47%
Peptide
41%
Hydrogen
36%
Isotope
17%
Dissociation
14%
Ligand
13%
Fucose
12%
Electrospray Ionization Mass Spectrometry
9%
Serine
9%
Rate Constant
6%
Hydrogen Bond
6%
Reaction Yield
4%