Drug accumulation in the presence of the multidrug resistance pump: dissociation between verapamil accumulation and the action of P-glycoprotein

Keyphrases

• Drug Accumulation 100%
• P-glycoprotein (P-gp) 100%
• Verapamil 100%
• Dissociation 100%
• Multidrug Resistance 100%
• Vinblastine 66%
• Steady State 33%
• P388 16%
• Daunomycin 16%
• Chloroquine 16%
• Multidrug-resistant 16%
• Leukemia Cell Lines 16%
• Multidrug Transporter 16%
• Intracellular Accumulation 16%
• Binding Site 16%
• Membrane Binding 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Multidrug Resistance 100%
• Verapamil 100%
• P-Glycoprotein 100%
• Vinblastine 66%
• Daunorubicin 16%
• Chloroquine 16%
• Binding Site 16%

Immunology and Microbiology

• P-Glycoprotein 100%
• Drug Accumulation 100%
• Multidrug Resistance 100%
• Steady State 33%
• Leukemia Cell Line 16%
• Chloroquine 16%
• Binding Site 16%