Does hyperbaric oxygen treatment have the potential to increase salivary flow rate and reduce xerostomia in previously irradiated head and neck cancer patients? A pilot study

Lone Forner, Ole Hyldegaard Hansen, Annet Schack von Brockdorff, Lena Specht, Elo Andersen, Erik C Jansen, Søren Hillerup, Birgitte Nauntofte, Siri Beier Jensen

19 Citationer (Scopus)

Abstract

Irradiated head and neck cancer survivors treated in the Hyperbaric Oxygen (HBO) Unit, Copenhagen University Hospital, spontaneously reported improvement of radiation-induced dry mouth feeling. The aim of this pilot study was to evaluate salivary flow rate and xerostomia before and after HBO in irradiated head and neck cancer patients. Eighty patients eligible for HBO treatment on the indication of prevention/treatment of osteoradionecrosis or soft tissue radiation injury were consecutively sampled, of whom 45 had hyposalivation (i.e. unstimulated whole saliva (UWS) flow rate
OriginalsprogEngelsk
TidsskriftOral Oncology
Vol/bind47
Udgave nummer6
Sider (fra-til)546-551
Antal sider6
ISSN1368-8375
DOI
StatusUdgivet - 1 jun. 2011

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