Diversity Oriented Approach toTriazole Based Peptidomimetics as Mammalian Sterile 20 Kinase Inhibitors

Keyphrases

• Kinase Inhibitor 100%
• Peptidomimetics 100%
• Drug Target 66%
• Triazole 66%
• Phosphoinositide 3-kinase (PI3K) 33%
• Docking Studies 33%
• Pro-apoptotic 33%
• Azides 33%
• Binding Mode 33%
• 1,3-dipolar Cycloaddition 33%
• Cardiomyopathy 33%
• Copper-catalyzed 33%
• Further Development 33%
• Serine-threonine Kinase 33%
• Serine-threonine Kinase Inhibitor 33%
• Kinase Profiling 33%
• IC50 Value 33%
• Alkynes 33%
• Pathological Conditions 33%
• Kinase Family 33%
• Protein Kinase 33%
• Small Molecule Inhibitors 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Phosphotransferase Inhibitor 100%
• Peptidomimetics 100%
• Mammalia 75%
• Phosphotransferase 75%
• Triazole 50%
• IC50 25%
• Azide 25%
• Protein Serine Threonine Kinase 25%
• Myocardial Disease 25%
• Protein Kinase 25%
• Protein Serine Threonine Kinase Inhibitor 25%
• Alkyne 25%

Biochemistry, Genetics and Molecular Biology

• Peptidomimetic 100%
• Kinase 100%
• Phosphotransferase 100%
• Mammalia 42%
• Serine 28%
• Threonine 28%
• Protein Kinase 14%
• Cycloaddition 14%
• IC50 14%
• Small Molecule 14%