Distribution of Y chromosome haplogroup Q in Greenlanders

TY - GEN

T1 - Distribution of Y chromosome haplogroup Q in Greenlanders

AU - Olofsson, Jill Katharina

AU - Børsting, Claus

AU - Morling, Niels

PY - 2013/10/28

Y1 - 2013/10/28

N2 - The Greenlandic population is characterised by migrations from two major areas: the northern parts of North America and Scandinavia. Y-chromosomal haplogroup (Y-HG) P*(xR1-M173)-M45 was previously found in up to 50% of Greenlanders. The aim of this study was to investigate the distribution of sub-HGs within Q-M242 in the Greenlandic population. A multiplex of 15 Y-chromosomal single nucleotide polymorphisms (Y-SNPs) covering major sub-HGs within Q-M242 was constructed using the AssayDesign software (Sequenom) and analysed on the Sequenom platform. Two sub-HGs within Q-M242 were found in the Greenlandic population, Q-L56, L57(xM19, M323, L529) and Q-NWT01(xM265). An increase of Inuit Y-HGs along the coastline from Qeqqata (30%) in the West to East Sermersooq (82%) was found. A corresponding decrease was found for European Y-HGs, from 59% in Qeqqata to 16% in East Sermersooq.

AB - The Greenlandic population is characterised by migrations from two major areas: the northern parts of North America and Scandinavia. Y-chromosomal haplogroup (Y-HG) P*(xR1-M173)-M45 was previously found in up to 50% of Greenlanders. The aim of this study was to investigate the distribution of sub-HGs within Q-M242 in the Greenlandic population. A multiplex of 15 Y-chromosomal single nucleotide polymorphisms (Y-SNPs) covering major sub-HGs within Q-M242 was constructed using the AssayDesign software (Sequenom) and analysed on the Sequenom platform. Two sub-HGs within Q-M242 were found in the Greenlandic population, Q-L56, L57(xM19, M323, L529) and Q-NWT01(xM265). An increase of Inuit Y-HGs along the coastline from Qeqqata (30%) in the West to East Sermersooq (82%) was found. A corresponding decrease was found for European Y-HGs, from 59% in Qeqqata to 16% in East Sermersooq.

M3 - Conference article

SN - 1875-1768

VL - 4

SP - e220-e221

JO - Forensic Science International: Genetics. Supplement Series

JF - Forensic Science International: Genetics. Supplement Series

IS - 1

T2 - 25’th congress of the International Society of Forensic Genetics

Y2 - 2 September 2013 through 7 September 2013

ER -