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Direct effects of cyclosporin A on human pancreatic beta-cells
T Mandrup-Poulsen
, J Nerup,
Jens Høiriis Nielsen
Inflammation, Metabolism and Oxidation
Endocrinology and Metabolism
130
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Keyphrases
Cyclosporine
100%
Human Pancreatic beta Cells
100%
Islet
55%
Endocrine Pancreas
22%
Insulin Release
22%
Insulin
22%
In Vivo Conditions
11%
Diabetes Mellitus Patients
11%
Insulin Content
11%
Rodents
11%
Glucagon
11%
Culture Time
11%
Clinical Remission
11%
Newly Diagnosed
11%
Non-insulin-dependent Diabetes Mellitus (NIDDM)
11%
Clinical Application
11%
Human Pancreatic Islets
11%
Adverse Effects
11%
High Dose
11%
Glucose-stimulated Insulin Secretion
11%
Immunomodulatory Effect
11%
Inhibitory Effect
11%
Medicine and Dentistry
Beta Cell
100%
Cyclosporine
100%
Insulin Release
37%
Endocrine Pancreas
25%
Adverse Effect
12%
Glucagon
12%
Drug Megadose
12%
Pancreatic Islet
12%
Immunosuppressive Drug
12%
Insulin Dependent Diabetes Mellitus
12%
Valspodar
12%
In Vitro
12%
Cyclosporin G
12%
Immunology and Microbiology
Ciclosporin
100%
Insulin
50%
Insulin Release
37%
Endocrine Pancreas
25%
Immunosuppressive Drug
12%
Glucagon
12%
Drug Megadose
12%
Biochemistry, Genetics and Molecular Biology
Ciclosporin
100%
Insulin Release
33%
Glucagon
11%
Drug Megadose
11%