TY - JOUR
T1 - Diagnostic stability of comorbid personality disorders among patients fully or partially remitted from first-episode depression
T2 - A 5-year follow-up study
AU - Bukh, Jens Drachmann
AU - Bech, Per
AU - Kessing, Lars Vedel
PY - 2017
Y1 - 2017
N2 - The diagnostic stability of comorbid personality disorders among patients with depression remains unclear. A total of 262 patients suffering from first-episode depression were assessed using the Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-II) and reassessed after 5 years. A total of 87 patients (33%) were diagnosed with a personality disorder at baseline, and 63 of them (72%) maintained a personality disorder diagnosis at follow-up (kappa coefficient 0.71). At cluster level, 63% maintained a diagnosis within cluster B and 48% maintained a cluster C disorder across the follow-up period (kappa coefficients of 0.54 and 0.64, respectively). Hence, comorbid personality disorders cannot be taken just as artifacts of the depressive mood that will remit spontaneously or with further treatment of the primary depression. Furthermore, the stability of personality disorders diagnoses was not predicted by clinical characteristics of the depression, nor of the course of the affective disorder during followup.
AB - The diagnostic stability of comorbid personality disorders among patients with depression remains unclear. A total of 262 patients suffering from first-episode depression were assessed using the Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-II) and reassessed after 5 years. A total of 87 patients (33%) were diagnosed with a personality disorder at baseline, and 63 of them (72%) maintained a personality disorder diagnosis at follow-up (kappa coefficient 0.71). At cluster level, 63% maintained a diagnosis within cluster B and 48% maintained a cluster C disorder across the follow-up period (kappa coefficients of 0.54 and 0.64, respectively). Hence, comorbid personality disorders cannot be taken just as artifacts of the depressive mood that will remit spontaneously or with further treatment of the primary depression. Furthermore, the stability of personality disorders diagnoses was not predicted by clinical characteristics of the depression, nor of the course of the affective disorder during followup.
U2 - 10.1521/pedi_2016_30_253
DO - 10.1521/pedi_2016_30_253
M3 - Journal article
C2 - 27322576
AN - SCOPUS:85018855419
SN - 0885-579X
VL - 31
SP - 208
EP - 220
JO - Journal of Personality Disorders
JF - Journal of Personality Disorders
IS - 2
ER -