Deterministic Group Tractography with Local Uncertainty Quantification

Andreas Nugaard Holm*, Aasa Feragen, Tom Dela Haije, Sune Darkner

*Corresponding author af dette arbejde

Abstract

While tractography is routinely used to trace the white-matter connectivity in individual subjects, the population analysis of tractography output is hampered by the difficulty of comparing populations of curves. As a result, analysis is often reduced to population summaries such as TBSS, or made pointwise with similar interaction of remote and nearby tracts. As an easy-to-use alternative, we propose population-wide tractography in MNI space, by simultaneously considering diffusion data from the entire population, registered to MNI. We include voxel-wise quantification of population variability as a measure of uncertainty. The group tractography algorithm is illustrated on a population of subjects from the Human Connectome Project, obtaining robust population estimates of the white matter tracts.

OriginalsprogEngelsk
TitelComputational Diffusion : International MICCAI Workshop, Granada,
RedaktørerElisenda Bonet-Carne, Francesco Grussu, Lipeng Ning, Farshid Sepehrband, Chantal M. W. Tax
ForlagSpringer
Publikationsdato2019
Udgave226249
Sider377-386
ISBN (Trykt)978-3-030-05830-2
ISBN (Elektronisk)978-3-030-05831-9
DOI
StatusUdgivet - 2019
BegivenhedInternational Workshop on Computational Diffusion MRI, CDMRI 2018 held with International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2018 - Granada, Spanien
Varighed: 20 sep. 201820 sep. 2018

Konference

KonferenceInternational Workshop on Computational Diffusion MRI, CDMRI 2018 held with International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2018
Land/OmrådeSpanien
ByGranada
Periode20/09/201820/09/2018
NavnMathematics and Visualization
ISSN1612-3786

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