Det kliniske forløb ved valproatforgiftning hos en treårig

Thalia Marie Blicher; Esben Thyssen Vestergaard; Kim Peder Dalhoff

Det kliniske forløb ved valproatforgiftning hos en treårig

Thalia Marie Blicher, Esben Thyssen Vestergaard, Kim Peder Dalhoff

Institut for Klinisk Medicin

Abstract

Valproic acid (VA) is an antiepileptic drug, and frequently prescribed in pediatrics. VA overdose results in central nervous system depression, insufficient respiration, tachycardia, hypotension, hepatotoxicity, and electrolyte derangement. We describe the clinical course of a three year-old girl after accidental intake of 6,000 mg VA. Treatment included activated charcoal. Clinical observation included measurements of blood pressure, cardiac telemetry, and measurements of serum VA and metabolic parameters every 4-6 hrs. The girl was discharged successfully after 72 hrs with her usual dose of VA.

Bidragets oversatte titel	The clinical course of a three year-old girl after overdose of valproic acid.
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	174
Udgave nummer	17
Sider (fra-til)	1165-1166
Antal sider	2
ISSN	0041-5782
Status	Udgivet - 2012

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http://ugeskriftet.dk/files/ugeskriftet.dk/artikel_4445.pdf

Citationsformater

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title = "Det kliniske forl{\o}b ved valproatforgiftning hos en tre{\aa}rig",

abstract = "Valproic acid (VA) is an antiepileptic drug, and frequently prescribed in pediatrics. VA overdose results in central nervous system depression, insufficient respiration, tachycardia, hypotension, hepatotoxicity, and electrolyte derangement. We describe the clinical course of a three year-old girl after accidental intake of 6,000 mg VA. Treatment included activated charcoal. Clinical observation included measurements of blood pressure, cardiac telemetry, and measurements of serum VA and metabolic parameters every 4-6 hrs. The girl was discharged successfully after 72 hrs with her usual dose of VA.",

author = "Blicher, {Thalia Marie} and Vestergaard, {Esben Thyssen} and Dalhoff, {Kim Peder}",

year = "2012",

language = "Dansk",

volume = "174",

pages = "1165--1166",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "17",

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TY - JOUR

T1 - Det kliniske forløb ved valproatforgiftning hos en treårig

AU - Blicher, Thalia Marie

AU - Vestergaard, Esben Thyssen

AU - Dalhoff, Kim Peder

PY - 2012

Y1 - 2012

N2 - Valproic acid (VA) is an antiepileptic drug, and frequently prescribed in pediatrics. VA overdose results in central nervous system depression, insufficient respiration, tachycardia, hypotension, hepatotoxicity, and electrolyte derangement. We describe the clinical course of a three year-old girl after accidental intake of 6,000 mg VA. Treatment included activated charcoal. Clinical observation included measurements of blood pressure, cardiac telemetry, and measurements of serum VA and metabolic parameters every 4-6 hrs. The girl was discharged successfully after 72 hrs with her usual dose of VA.

AB - Valproic acid (VA) is an antiepileptic drug, and frequently prescribed in pediatrics. VA overdose results in central nervous system depression, insufficient respiration, tachycardia, hypotension, hepatotoxicity, and electrolyte derangement. We describe the clinical course of a three year-old girl after accidental intake of 6,000 mg VA. Treatment included activated charcoal. Clinical observation included measurements of blood pressure, cardiac telemetry, and measurements of serum VA and metabolic parameters every 4-6 hrs. The girl was discharged successfully after 72 hrs with her usual dose of VA.

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 174

SP - 1165

EP - 1166

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 17

ER -

Det kliniske forløb ved valproatforgiftning hos en treårig

Abstract

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