@article{1db8b804394c41fb934d2d921994de7b,
title = "Design and synthesis of a stable oxidized phospholipid mimic with specific binding recognition for macrophage scavenger receptors",
abstract = "Macrophage scavenger receptors appear to play a major role in the clearance of oxidized phospholipid (OxPL) products. Discrete peptide-phospholipid conjugates with the phosphatidylcholine headgroup have been shown to exhibit binding affinity for these receptors. We report the preparation of a water-soluble, stable peptide-phospholipid conjugate (9) that possesses the necessary physical properties to enable more detailed study of the role(s) of OxPL in metabolic disease.",
keywords = "Animals, Antibodies, Monoclonal, Antigens, CD36, Biomimetic Materials, Chemistry Techniques, Synthetic, Drug Design, Drug Stability, Humans, Mice, Oxidation-Reduction, Phospholipid Ethers, Protein Binding, Solubility, Substrate Specificity, Water",
author = "Turner, {William W} and Karsten Hartvigsen and Agnes Boullier and Montano, {Erica N} and Witztum, {Joseph L} and VanNieuwenhze, {Michael S}",
year = "2012",
month = sep,
day = "27",
doi = "10.1021/jm300685s",
language = "English",
volume = "55",
pages = "8178--82",
journal = "Journal of Medicinal Chemistry",
issn = "0022-2623",
publisher = "American Chemical Society",
number = "18",
}