Dermatosis in children with oedematous malnutrition (Kwashiorkor): A review of the literature

TY - JOUR

T1 - Dermatosis in children with oedematous malnutrition (Kwashiorkor)

T2 - A review of the literature

AU - Heilskov, S

AU - Rytter, Maren Johanne Heilskov

AU - Vestergaard, C

AU - Briend, A

AU - Babirekere, E

AU - Deleuran, M S

N1 - CURIS 2014 NEXS 269

PY - 2014/8

Y1 - 2014/8

N2 - Children with oedematous malnutrition, known as kwashiorkor, may develop a characteristic skin lesion, named 'Dermatosis of Kwashiorkor' (DoK). Only a few studies have been concerned with this condition, and the reason for the development of DoK remains unexplained. This study review the existing studies concerning DoK, including its clinical manifestations, histopathology, suggested pathophysiology, current treatment and prognosis for children of the age of 6 months to 5 years. Standardized clinical studies are needed to further understand the implications of DoK. Such studies would suffer from the lack of consistency concerning the terminology and scoring of the lesions in DoK. We therefore stress the need for a standardized scoring of the degree of DoK. This would facilitate valid and comparable studies and the development of better treatment for this vulnerable group of patients.

AB - Children with oedematous malnutrition, known as kwashiorkor, may develop a characteristic skin lesion, named 'Dermatosis of Kwashiorkor' (DoK). Only a few studies have been concerned with this condition, and the reason for the development of DoK remains unexplained. This study review the existing studies concerning DoK, including its clinical manifestations, histopathology, suggested pathophysiology, current treatment and prognosis for children of the age of 6 months to 5 years. Standardized clinical studies are needed to further understand the implications of DoK. Such studies would suffer from the lack of consistency concerning the terminology and scoring of the lesions in DoK. We therefore stress the need for a standardized scoring of the degree of DoK. This would facilitate valid and comparable studies and the development of better treatment for this vulnerable group of patients.

U2 - 10.1111/jdv.12452

DO - 10.1111/jdv.12452

M3 - Review

C2 - 24661336

SN - 0926-9959

VL - 28

SP - 995

EP - 1001

JO - Journal of the European Academy of Dermatology and Venereology

JF - Journal of the European Academy of Dermatology and Venereology

IS - 8

ER -