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Degradation of hyaluronic acid, poly- and monosaccharides, and model compounds by hypochlorite: evidence for radical intermediates and fragmentation
C L Hawkins,
Michael Jonathan Davies
Inflammation, Metabolism and Oxidation
103
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Medicin og biovidenskab
Hypochlorous Acid
100%
Monosaccharides
89%
Hyaluronic Acid
73%
Polysaccharides
65%
Chondroitin Sulfates
56%
Carbon
34%
Acetylglucosamine
30%
Amides
27%
Nitrogen
22%
Sugars
22%
Polymers
20%
alkoxyl radical
19%
Sugar Acids
18%
Spin Trapping
17%
Oxidants
12%
Spectrum Analysis
11%
Molecular Weight
9%
Rheumatoid Arthritis
9%
Electrons
9%
Kemiske forbindelser
Hypochlorite
85%
Hyaluronic Acid
79%
Monosaccharide
73%
Fragmentation
57%
Chondroitin Sulfate
42%
N-Acetyl Group
35%
N-Acetylglucosamine
28%
Ultraviolet Spectrum
18%
Adduct
16%
Amide
16%
Homolysis
14%
Spin Trapping
13%
EPR Spectroscopy
10%
Polysaccharide
9%
Electron Spin
9%
Reduction
5%
Reaction Yield
4%