Decomposition of number of life years lost according to causes of death

Per Kragh Andersen

Decomposition of number of life years lost according to causes of death

Biostatistisk afdeling

53 Citationer (Scopus)

Abstract

We study the competing risks model and show that the cause j cumulative incidence function integrated from 0 to τ has a natural interpretation as the expected number of life years lost due to cause j before time τ. This is analogous to the τ-restricted mean lifetime, which is the survival function integrated from 0 to τ. It is discussed how the number of years lost may be related to subject-specific explanatory variables in a regression model based on pseudo-observations, and the method is exemplified using data from a bone marrow transplantation study. Finally, inclusion of standard mortality rates is discussed.

Originalsprog	Udefineret/Ukendt
Tidsskrift	Statistics in Medicine
Vol/bind	32
Udgave nummer	30
Sider (fra-til)	5278-5285
Antal sider	8
ISSN	0277-6715
Status	Udgivet - 30 dec. 2013

Citationsformater

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AB - We study the competing risks model and show that the cause j cumulative incidence function integrated from 0 to τ has a natural interpretation as the expected number of life years lost due to cause j before time τ. This is analogous to the τ-restricted mean lifetime, which is the survival function integrated from 0 to τ. It is discussed how the number of years lost may be related to subject-specific explanatory variables in a regression model based on pseudo-observations, and the method is exemplified using data from a bone marrow transplantation study. Finally, inclusion of standard mortality rates is discussed.

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