Cultivation of Artemisia annua—the environmental perspective

Karina Knudsmark Sjøholm; Bjarne W. Strobel; Nina Cedergreen

doi:10.1201/b22102

Cultivation of Artemisia annua—the environmental perspective

Karina Knudsmark Sjøholm, Bjarne W. Strobel, Nina Cedergreen

Miljøkemi

Abstract

Bioactive secondary metabolites represent a wide range of different chemical compounds, but the three major classes are nitrogen-containing compounds, phenols, and terpenes. Artemisinin, produced by Artemisia annua L. (sweet wormwood, annual wormwood, sweet annie, sweet sagewort) belongs to the terpenes group. Artemisinin is a sesquiterpene lactone with an endoperoxide bridge (Liu et al., 1979), and is very bioactive against chloroquine-resistant strains of the malaria parasite Plasmodium falciparum (Klayman, 1985). Today, combination therapies containing artemisinin are recommended as the first-line treatment for malaria in 77 out of 80 countries and amounted to 311 million treatments worldwide in 2015 (WHO, 2015).

Originalsprog	Engelsk
Titel	Artemisia Annua : Prospects, Applications and Therapeutic Uses
Forlag	CRC Press
Publikationsdato	2017
Sider	131-154
Kapitel	7
ISBN (Trykt)	9781138632103
ISBN (Elektronisk)	9781351802864
DOI	https://doi.org/10.1201/b22102
Status	Udgivet - 2017

FN’s Verdensmål

Dette resultat bidrager til følgende verdensmål

Adgang til dokumentet

10.1201/b22102

Andre filer og links

Link to publication in Scopus

Citationsformater

@inbook{ccf09196825d413fafac8757cd143666,

title = "Cultivation of Artemisia annua—the environmental perspective",

abstract = "Bioactive secondary metabolites represent a wide range of different chemical compounds, but the three major classes are nitrogen-containing compounds, phenols, and terpenes. Artemisinin, produced by Artemisia annua L. (sweet wormwood, annual wormwood, sweet annie, sweet sagewort) belongs to the terpenes group. Artemisinin is a sesquiterpene lactone with an endoperoxide bridge (Liu et al., 1979), and is very bioactive against chloroquine-resistant strains of the malaria parasite Plasmodium falciparum (Klayman, 1985). Today, combination therapies containing artemisinin are recommended as the first-line treatment for malaria in 77 out of 80 countries and amounted to 311 million treatments worldwide in 2015 (WHO, 2015).",

author = "Sj{\o}holm, {Karina Knudsmark} and Strobel, {Bjarne W.} and Nina Cedergreen",

year = "2017",

doi = "10.1201/b22102",

language = "English",

isbn = "9781138632103",

pages = "131--154",

booktitle = "Artemisia Annua",

publisher = "CRC Press",

}

TY - CHAP

T1 - Cultivation of Artemisia annua—the environmental perspective

AU - Sjøholm, Karina Knudsmark

AU - Strobel, Bjarne W.

AU - Cedergreen, Nina

PY - 2017

Y1 - 2017

N2 - Bioactive secondary metabolites represent a wide range of different chemical compounds, but the three major classes are nitrogen-containing compounds, phenols, and terpenes. Artemisinin, produced by Artemisia annua L. (sweet wormwood, annual wormwood, sweet annie, sweet sagewort) belongs to the terpenes group. Artemisinin is a sesquiterpene lactone with an endoperoxide bridge (Liu et al., 1979), and is very bioactive against chloroquine-resistant strains of the malaria parasite Plasmodium falciparum (Klayman, 1985). Today, combination therapies containing artemisinin are recommended as the first-line treatment for malaria in 77 out of 80 countries and amounted to 311 million treatments worldwide in 2015 (WHO, 2015).

AB - Bioactive secondary metabolites represent a wide range of different chemical compounds, but the three major classes are nitrogen-containing compounds, phenols, and terpenes. Artemisinin, produced by Artemisia annua L. (sweet wormwood, annual wormwood, sweet annie, sweet sagewort) belongs to the terpenes group. Artemisinin is a sesquiterpene lactone with an endoperoxide bridge (Liu et al., 1979), and is very bioactive against chloroquine-resistant strains of the malaria parasite Plasmodium falciparum (Klayman, 1985). Today, combination therapies containing artemisinin are recommended as the first-line treatment for malaria in 77 out of 80 countries and amounted to 311 million treatments worldwide in 2015 (WHO, 2015).

UR - http://www.scopus.com/inward/record.url?scp=85054220477&partnerID=8YFLogxK

U2 - 10.1201/b22102

DO - 10.1201/b22102

M3 - Book chapter

AN - SCOPUS:85054220477

SN - 9781138632103

SP - 131

EP - 154

BT - Artemisia Annua

PB - CRC Press

ER -

Cultivation of Artemisia annua—the environmental perspective

Abstract

FN’s Verdensmål

Adgang til dokumentet

Andre filer og links

Fingeraftryk

Citationsformater