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Cooperative stabilization of the SIR complex provides robust epigenetic memory in a model of SIR silencing in Saccharomyces cerevisiae
Kim Sneppen
, Ian B. Dodd
Biokompleksitet
8
Citationer (Scopus)
59
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Keyphrases
Saccharomyces Cerevisiae
100%
Epigenetic Memory
100%
Anti-silencing
100%
Bistability
66%
Sir2
66%
Chromatin
66%
Silencer
66%
Positive Feedback
66%
Double Negative
33%
Feedback Response
33%
Containment
33%
H3K79me2
33%
Histone Modification
33%
Methylation
33%
Negative Feedback Loop
33%
Epigenetic Regulation
33%
Nucleosome Binding
33%
Cooperative Interaction
33%
Cooperative Binding
33%
Stochastic Model
33%
Cooperativity
33%
Histone Acetylation
33%
Biochemistry, Genetics and Molecular Biology
Epigenetics
100%
baker's yeast
100%
Nucleosome
66%
Sir2
66%
Positive Feedback
66%
Cooperative Binding
33%
Silencer Element
33%
Methylation
33%
Histone Modification
33%
Histone
33%
Product Inhibition
33%
Cooperation
33%
Deacetylation
33%