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Conformational changes in DNA gyrase revealed by limited proteolysis
S C Kampranis
, A Maxwell
Plantebiokemi
52
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Biochemistry, Genetics and Molecular Biology
Proteolysis
100%
DNA Gyrase
100%
Gyrase
100%
Conformational Change
100%
Enzyme
60%
Adenosine Triphosphate
60%
Dimerization
60%
Calcium Ion
20%
N-Terminus
20%
Conformation
20%
Enzymatic Hydrolysis
20%
C-Terminus
20%
Active Site
20%
Keyphrases
DNA Gyrase
100%
Limited Proteolysis
100%
Quinolones
100%
Conformational Change
100%
Gyrase
55%
Dimerization
33%
DNA Complex
22%
β Subunit
22%
Active Site mutant
11%
Conformational States
11%
Hydrolysable
11%
Resistant mutants
11%
Incubation
11%
ATP Analogues
11%
Kinetic Characteristics
11%
N-terminal Domain
11%
Beta-gamma
11%
Characteristic Signature
11%
Calcium Ion
11%