Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

on behalf of the ICON and SOAP investigators; SOAP investigators

doi:10.1007/s00134-017-5043-2

Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

on behalf of the ICON and SOAP investigators, SOAP investigators

Institut for Klinisk Medicin

57 Citationer (Scopus)

30 Downloads (Pure)

Abstract

Purpose: To evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time. Methods: We reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study, an observational study conducted in European intensive care units in 2002, and the Intensive Care Over Nations (ICON) audit, a survey of intensive care unit patients conducted in 2012. Results: We compared the 3147 patients from the SOAP study with the 4852 patients from the ICON audit admitted to intensive care units in the same countries as those in the SOAP study. The ICON patients were older (62.5 ± 17.0 vs. 60.6 ± 17.4 years) and had higher severity scores than the SOAP patients. The proportion of patients with sepsis at any time during the intensive care unit stay was slightly higher in the ICON study (31.9 vs. 29.6%, p = 0.03). In multilevel analysis, the adjusted odds of ICU mortality were significantly lower for ICON patients than for SOAP patients, particularly in patients with sepsis [OR 0.45 (0.35–0.59), p < 0.001]. Conclusions: Over the 10-year period between 2002 and 2012, the proportion of patients with sepsis admitted to European ICUs remained relatively stable, but the severity of disease increased. In multilevel analysis, the odds of ICU mortality were lower in our 2012 cohort compared to our 2002 cohort, particularly in patients with sepsis.

Originalsprog	Engelsk
Tidsskrift	Intensive Care Medicine
Vol/bind	44
Udgave nummer	3
Sider (fra-til)	337-344
Antal sider	8
ISSN	0342-4642
DOI	https://doi.org/10.1007/s00134-017-5043-2
Status	Udgivet - 2018

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10.1007/s00134-017-5043-2Licens: CC BY-NC

Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)Forlagets udgivne version, 868 KBLicens: CC BY-NC

Citationsformater

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title = "Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)",

abstract = "Purpose: To evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time. Methods: We reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study, an observational study conducted in European intensive care units in 2002, and the Intensive Care Over Nations (ICON) audit, a survey of intensive care unit patients conducted in 2012. Results: We compared the 3147 patients from the SOAP study with the 4852 patients from the ICON audit admitted to intensive care units in the same countries as those in the SOAP study. The ICON patients were older (62.5 ± 17.0 vs. 60.6 ± 17.4 years) and had higher severity scores than the SOAP patients. The proportion of patients with sepsis at any time during the intensive care unit stay was slightly higher in the ICON study (31.9 vs. 29.6%, p = 0.03). In multilevel analysis, the adjusted odds of ICU mortality were significantly lower for ICON patients than for SOAP patients, particularly in patients with sepsis [OR 0.45 (0.35–0.59), p < 0.001]. Conclusions: Over the 10-year period between 2002 and 2012, the proportion of patients with sepsis admitted to European ICUs remained relatively stable, but the severity of disease increased. In multilevel analysis, the odds of ICU mortality were lower in our 2012 cohort compared to our 2002 cohort, particularly in patients with sepsis.",

keywords = "Epidemiology, Sepsis, Severity of disease",

author = "Vincent, {Jean Louis} and Lefrant, {Jean Yves} and Katarzyna Kotfis and Rahul Nanchal and Ignacio Martin-Loeches and Xavier Wittebole and Sakka, {Samir G.} and Peter Pickkers and Rui Moreno and Yasser Sakr and P. Pavlik and J. Manak and E. Kieslichova and R. Turek and M. Fischer and R. Valkova and L. Dadak and P. Dostal and J. Malaska and R. Hajek and A. {\v Z}idkov{\'a} and P. Lavicka and L. Medve and A. Sarkany and I. Kremer and Z. Marjanek and P. Tamasi and J. Kolbusz and A. K{\"u}bler and B. Mielczarek and M. Mikaszewska-Sokolewicz and B. Tamowicz and W. Sulkowski and P. Smuszkiewicz and A. Pihowicz and E. Trejnowska and N. Hagau and D. Filipescu and G. Droc and M. Lupu and A. Nica and R. Stoica and D. Tomescu and D. Constantinescu and A. Lerche and M. Bestle and H. Guldager and Welling, {K. L.} and R. Gatz and A. Keller and {on behalf of the ICON and SOAP investigators} and {SOAP investigators}",

year = "2018",

doi = "10.1007/s00134-017-5043-2",

language = "English",

volume = "44",

pages = "337--344",

journal = "European Journal of Intensive Care Medicine",

issn = "0935-1701",

publisher = "Springer",

number = "3",

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TY - JOUR

T1 - Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

AU - Vincent, Jean Louis

AU - Lefrant, Jean Yves

AU - Kotfis, Katarzyna

AU - Nanchal, Rahul

AU - Martin-Loeches, Ignacio

AU - Wittebole, Xavier

AU - Sakka, Samir G.

AU - Pickkers, Peter

AU - Moreno, Rui

AU - Sakr, Yasser

AU - Pavlik, P.

AU - Manak, J.

AU - Kieslichova, E.

AU - Turek, R.

AU - Fischer, M.

AU - Valkova, R.

AU - Dadak, L.

AU - Dostal, P.

AU - Malaska, J.

AU - Hajek, R.

AU - Židková, A.

AU - Lavicka, P.

AU - Medve, L.

AU - Sarkany, A.

AU - Kremer, I.

AU - Marjanek, Z.

AU - Tamasi, P.

AU - Kolbusz, J.

AU - Kübler, A.

AU - Mielczarek, B.

AU - Mikaszewska-Sokolewicz, M.

AU - Tamowicz, B.

AU - Sulkowski, W.

AU - Smuszkiewicz, P.

AU - Pihowicz, A.

AU - Trejnowska, E.

AU - Hagau, N.

AU - Filipescu, D.

AU - Droc, G.

AU - Lupu, M.

AU - Nica, A.

AU - Stoica, R.

AU - Tomescu, D.

AU - Constantinescu, D.

AU - Lerche, A.

AU - Bestle, M.

AU - Guldager, H.

AU - Welling, K. L.

AU - Gatz, R.

AU - Keller, A.

AU - on behalf of the ICON and SOAP investigators

AU - SOAP investigators

PY - 2018

Y1 - 2018

N2 - Purpose: To evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time. Methods: We reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study, an observational study conducted in European intensive care units in 2002, and the Intensive Care Over Nations (ICON) audit, a survey of intensive care unit patients conducted in 2012. Results: We compared the 3147 patients from the SOAP study with the 4852 patients from the ICON audit admitted to intensive care units in the same countries as those in the SOAP study. The ICON patients were older (62.5 ± 17.0 vs. 60.6 ± 17.4 years) and had higher severity scores than the SOAP patients. The proportion of patients with sepsis at any time during the intensive care unit stay was slightly higher in the ICON study (31.9 vs. 29.6%, p = 0.03). In multilevel analysis, the adjusted odds of ICU mortality were significantly lower for ICON patients than for SOAP patients, particularly in patients with sepsis [OR 0.45 (0.35–0.59), p < 0.001]. Conclusions: Over the 10-year period between 2002 and 2012, the proportion of patients with sepsis admitted to European ICUs remained relatively stable, but the severity of disease increased. In multilevel analysis, the odds of ICU mortality were lower in our 2012 cohort compared to our 2002 cohort, particularly in patients with sepsis.

AB - Purpose: To evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time. Methods: We reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study, an observational study conducted in European intensive care units in 2002, and the Intensive Care Over Nations (ICON) audit, a survey of intensive care unit patients conducted in 2012. Results: We compared the 3147 patients from the SOAP study with the 4852 patients from the ICON audit admitted to intensive care units in the same countries as those in the SOAP study. The ICON patients were older (62.5 ± 17.0 vs. 60.6 ± 17.4 years) and had higher severity scores than the SOAP patients. The proportion of patients with sepsis at any time during the intensive care unit stay was slightly higher in the ICON study (31.9 vs. 29.6%, p = 0.03). In multilevel analysis, the adjusted odds of ICU mortality were significantly lower for ICON patients than for SOAP patients, particularly in patients with sepsis [OR 0.45 (0.35–0.59), p < 0.001]. Conclusions: Over the 10-year period between 2002 and 2012, the proportion of patients with sepsis admitted to European ICUs remained relatively stable, but the severity of disease increased. In multilevel analysis, the odds of ICU mortality were lower in our 2012 cohort compared to our 2002 cohort, particularly in patients with sepsis.

KW - Epidemiology

KW - Sepsis

KW - Severity of disease

U2 - 10.1007/s00134-017-5043-2

DO - 10.1007/s00134-017-5043-2

M3 - Journal article

C2 - 29450593

AN - SCOPUS:85042129933

SN - 0935-1701

VL - 44

SP - 337

EP - 344

JO - European Journal of Intensive Care Medicine

JF - European Journal of Intensive Care Medicine

IS - 3

ER -

Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

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