Chromium allergy and dermatitis: prevalence and main findings

David Kaspar Bregnbak; Jeanne Duus Johansen; Morten S Jellesen; Claus Zachariae; Torkil Menné; Jacob Pontoppidan Thyssen

doi:10.1111/cod.12436

Chromium allergy and dermatitis: prevalence and main findings

David Kaspar Bregnbak, Jeanne Duus Johansen, Morten S Jellesen, Claus Zachariae, Torkil Menné, Jacob Pontoppidan Thyssen

Institut for Klinisk Medicin

54 Citationer (Scopus)

Abstract

Summary The history of chromium as an allergen goes back more than a century, and includes an interventional success with national legislation that led to significant changes in the epidemiology of chromium allergy in construction workers. The 2015 EU Leather Regulation once again put a focus on chromium allergy, emphasizing that the investigation of chromium allergy is still far from complete. Our review article on chromium focuses on the allergen's chemical properties, its potential exposure sources, and the allergen's interaction with the skin, and also provides an overview of the regulations, and analyses the epidemiological pattern between nations and across continents. We provide an update on the allergen from a dermatological point of view, and conclude that much still remains to be discovered about the allergen, and that continued surveillance of exposure sources and prevalence rates is necessary.

Originalsprog	Engelsk
Tidsskrift	Contact Dermatitis
Vol/bind	73
Udgave nummer	5
Sider (fra-til)	261-80
Antal sider	20
ISSN	0105-1873
DOI	https://doi.org/10.1111/cod.12436
Status	Udgivet - nov. 2015

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10.1111/cod.12436

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cod.12436

Citationsformater

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AU - Bregnbak, David Kaspar

AU - Johansen, Jeanne Duus

AU - Jellesen, Morten S

AU - Zachariae, Claus

AU - Menné, Torkil

AU - Thyssen, Jacob Pontoppidan

PY - 2015/11

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N2 - Summary The history of chromium as an allergen goes back more than a century, and includes an interventional success with national legislation that led to significant changes in the epidemiology of chromium allergy in construction workers. The 2015 EU Leather Regulation once again put a focus on chromium allergy, emphasizing that the investigation of chromium allergy is still far from complete. Our review article on chromium focuses on the allergen's chemical properties, its potential exposure sources, and the allergen's interaction with the skin, and also provides an overview of the regulations, and analyses the epidemiological pattern between nations and across continents. We provide an update on the allergen from a dermatological point of view, and conclude that much still remains to be discovered about the allergen, and that continued surveillance of exposure sources and prevalence rates is necessary.

AB - Summary The history of chromium as an allergen goes back more than a century, and includes an interventional success with national legislation that led to significant changes in the epidemiology of chromium allergy in construction workers. The 2015 EU Leather Regulation once again put a focus on chromium allergy, emphasizing that the investigation of chromium allergy is still far from complete. Our review article on chromium focuses on the allergen's chemical properties, its potential exposure sources, and the allergen's interaction with the skin, and also provides an overview of the regulations, and analyses the epidemiological pattern between nations and across continents. We provide an update on the allergen from a dermatological point of view, and conclude that much still remains to be discovered about the allergen, and that continued surveillance of exposure sources and prevalence rates is necessary.

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DO - 10.1111/cod.12436

M3 - Review

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VL - 73

SP - 261

EP - 280

JO - Contact Dermatitis

JF - Contact Dermatitis

IS - 5

ER -

Chromium allergy and dermatitis: prevalence and main findings

Abstract

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