TY - JOUR
T1 - Changes in antimicrobial susceptibility patterns of Klebsiella pneumoniae, Escherichia coli and Staphylococcus aureus over the past decade
AU - Barfod, Toke Seierøe
AU - Wibroe, Elisabeth Arnberg
AU - Braüner, Julie Vestergaard
AU - Knudsen, Jenny Dahl
PY - 2015/9
Y1 - 2015/9
N2 - INTRODUCTION: Development of antimicrobial resistance is an ongoing and increasing problem. To provide the best possible treatment for patients it is crucial that clinicians are aware of the local antimicrobial susceptibility patterns. The aim of this study was to present an overview of the percentage of bacterial isolates that are covered by the most commonly used antibiotics in the area of Copenhagen and to provide clinicians with a practical tool to help chose the right antimicrobial treatment for their patients. METHODS: We conducted a study of all bacteria isolates tested for antimicrobial susceptibility at Hvidovre Hospital, Denmark, from 2004 to 2008. Due to a suspected rise in resistance in Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae after this period, updated data for these bacteria are shown for selected antibiotics until 2014. The department receives samples from hospitals as well as from primary health care. Only one isolate per species per patient per year was included. RESULTS: A total of 224,033 bacteria isolates were included in this study. The antimicrobial susceptibility of the various bacteria is presented in a table. No clinically relevant changes in resistance patterns were noted up to 2014. CONCLUSIONS: A comprehensive and manageable inventory of the resistance patterns of the major bacteria covering the 2004-2008 period is presented. Clinicians are encouraged to use the pocket-size table as guidance when choosing antibiotic treatment.
AB - INTRODUCTION: Development of antimicrobial resistance is an ongoing and increasing problem. To provide the best possible treatment for patients it is crucial that clinicians are aware of the local antimicrobial susceptibility patterns. The aim of this study was to present an overview of the percentage of bacterial isolates that are covered by the most commonly used antibiotics in the area of Copenhagen and to provide clinicians with a practical tool to help chose the right antimicrobial treatment for their patients. METHODS: We conducted a study of all bacteria isolates tested for antimicrobial susceptibility at Hvidovre Hospital, Denmark, from 2004 to 2008. Due to a suspected rise in resistance in Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae after this period, updated data for these bacteria are shown for selected antibiotics until 2014. The department receives samples from hospitals as well as from primary health care. Only one isolate per species per patient per year was included. RESULTS: A total of 224,033 bacteria isolates were included in this study. The antimicrobial susceptibility of the various bacteria is presented in a table. No clinically relevant changes in resistance patterns were noted up to 2014. CONCLUSIONS: A comprehensive and manageable inventory of the resistance patterns of the major bacteria covering the 2004-2008 period is presented. Clinicians are encouraged to use the pocket-size table as guidance when choosing antibiotic treatment.
KW - Anti-Bacterial Agents
KW - Bacterial Infections
KW - Denmark
KW - Drug Resistance, Bacterial
KW - Escherichia coli
KW - Humans
KW - Klebsiella pneumoniae
KW - Microbial Sensitivity Tests
KW - Staphylococcus aureus
KW - Journal Article
M3 - Journal article
C2 - 26441391
SN - 2245-1919
VL - 62
JO - Danish Medical Journal
JF - Danish Medical Journal
IS - 10
M1 - A5145
ER -