Cerebral blood flow in volunteers measured by PET and Xe CT/CBF. A comparison.

TY - JOUR

T1 - Cerebral blood flow in volunteers measured by PET and Xe CT/CBF. A comparison.

AU - Bergholt, B

AU - Ostergaard, L

AU - von Oettingen, G

AU - Johannsen, P

AU - Poulsen, P H

AU - Bundgaard, H

AU - Asboe, H

AU - Cold, G E

AU - Gjedde, A

AU - Gyldensted, C

AU - Astrup, J

PY - 2000

Y1 - 2000

N2 - Aim of this study was to compare two quantitative CBF methods. Seven young, healthy volunteers were studied with PET (15-0 labelled water) and afterwards with Xe CT/CBF (30% xenon in oxygen, 3 minutes wash-in, 5 minutes washout protocol). Xe CT/CBF showed greater differences between high and low flow areas than PET CBF. Correlation was found within subjects between ROI's, but no agreement or correlation between the methods could be demonstrated. The disagreement in this study could be due to changes in PCO2.

AB - Aim of this study was to compare two quantitative CBF methods. Seven young, healthy volunteers were studied with PET (15-0 labelled water) and afterwards with Xe CT/CBF (30% xenon in oxygen, 3 minutes wash-in, 5 minutes washout protocol). Xe CT/CBF showed greater differences between high and low flow areas than PET CBF. Correlation was found within subjects between ROI's, but no agreement or correlation between the methods could be demonstrated. The disagreement in this study could be due to changes in PCO2.

M3 - Journal article

C2 - 10750338

SN - 0022-9717

VL - 49 Suppl 1

SP - A55-7

JO - Keio Journal of Medicine

JF - Keio Journal of Medicine

ER -