Cancer in Drosophila: Imaginal Discs as a Model for Epithelial Tumor Formation

TY - JOUR

T1 - Cancer in Drosophila

T2 - Imaginal Discs as a Model for Epithelial Tumor Formation

AU - Herranz, Héctor

AU - Eichenlaub, Teresa

AU - Cohen, Stephen M

N1 - Chapter 11 in Essays on Developmental Biology, Part A Edited by Paul M. Wassarman ISBN: 978-0-12-802956-5

PY - 2016

Y1 - 2016

N2 - Cancer genomics has greatly increased our understanding of the complexity of the genetic and epigenetic changes found in human tumors. Understanding the functional relationships among these elements calls for the use of flexible genetic models. We discuss the use of Drosophila models to study cooperation among genetic factors that contribute to disease progression.

AB - Cancer genomics has greatly increased our understanding of the complexity of the genetic and epigenetic changes found in human tumors. Understanding the functional relationships among these elements calls for the use of flexible genetic models. We discuss the use of Drosophila models to study cooperation among genetic factors that contribute to disease progression.

U2 - 10.1016/bs.ctdb.2015.11.037

DO - 10.1016/bs.ctdb.2015.11.037

M3 - Journal article

C2 - 26970620

SN - 0070-2153

VL - 116

SP - 181

EP - 199

JO - Current Topics in Developmental Biology

JF - Current Topics in Developmental Biology

ER -