Campylobacter, Salmonella, and Yersinia antibodies and pregnancy outcome in Danish women with occupational exposure to animals

Bjørn Kantsø; Anne-Marie Nybo Andersen; Kåre Mølbak; Karen Angeliki Krogfelt; Tine Brink Henriksen; Stine Yde Nielsen

doi:10.1016/j.ijid.2014.06.021

Campylobacter, Salmonella, and Yersinia antibodies and pregnancy outcome in Danish women with occupational exposure to animals

Bjørn Kantsø, Anne-Marie Nybo Andersen, Kåre Mølbak, Karen Angeliki Krogfelt, Tine Brink Henriksen, Stine Yde Nielsen

https://www.ifsv.ku.dk/om-instituttet/socialmedicin/

2 Citationer (Scopus)

Abstract

BACKGROUND: The aim of this study was to determine antibody titres against Campylobacter, Salmonella, and Yersinia in a population-based cohort of pregnant women in Denmark in order to evaluate adverse pregnancy outcomes (miscarriage, preterm birth, and small for gestational age) in relation to occupational exposure to animals in women exposed to food producing animals.

METHODS: We used data and blood samples from the Danish National Birth Cohort. Serum samples collected during the first trimester from 192 pregnant women who were occupationally exposed to domestic animals and 188 randomly selected unexposed pregnant women were analysed for IgG, IgM, and IgA antibodies against Campylobacter, Salmonella, and Yersinia. Pregnancy outcomes of interest were identified through the Danish National Patient Register.

RESULTS: Women with occupational exposure to animals had significantly higher IgG antibody concentrations against Campylobacter, Salmonella, and Yersinia, whereas they had lower concentrations of IgM and IgA antibodies.

CONCLUSIONS: Serological markers were not identified as risk factors for adverse pregnancy outcomes, with the exception of elevated concentrations of Salmonella antibodies, which were found to be associated with an increased risk of preterm birth.

Originalsprog	Engelsk
Tidsskrift	International Journal of Infectious Diseases
Vol/bind	28
Sider (fra-til)	74-9
Antal sider	6
ISSN	1201-9712
DOI	https://doi.org/10.1016/j.ijid.2014.06.021
Status	Udgivet - 1 nov. 2014

Adgang til dokumentet

10.1016/j.ijid.2014.06.021

Citationsformater

@article{d6b5a4244f974f6aad3099f2d43bb391,

title = "Campylobacter, Salmonella, and Yersinia antibodies and pregnancy outcome in Danish women with occupational exposure to animals",

abstract = "BACKGROUND: The aim of this study was to determine antibody titres against Campylobacter, Salmonella, and Yersinia in a population-based cohort of pregnant women in Denmark in order to evaluate adverse pregnancy outcomes (miscarriage, preterm birth, and small for gestational age) in relation to occupational exposure to animals in women exposed to food producing animals.METHODS: We used data and blood samples from the Danish National Birth Cohort. Serum samples collected during the first trimester from 192 pregnant women who were occupationally exposed to domestic animals and 188 randomly selected unexposed pregnant women were analysed for IgG, IgM, and IgA antibodies against Campylobacter, Salmonella, and Yersinia. Pregnancy outcomes of interest were identified through the Danish National Patient Register.RESULTS: Women with occupational exposure to animals had significantly higher IgG antibody concentrations against Campylobacter, Salmonella, and Yersinia, whereas they had lower concentrations of IgM and IgA antibodies.CONCLUSIONS: Serological markers were not identified as risk factors for adverse pregnancy outcomes, with the exception of elevated concentrations of Salmonella antibodies, which were found to be associated with an increased risk of preterm birth.",

author = "Bj{\o}rn Kants{\o} and Andersen, {Anne-Marie Nybo} and K{\aa}re M{\o}lbak and Krogfelt, {Karen Angeliki} and Henriksen, {Tine Brink} and Nielsen, {Stine Yde}",

year = "2014",

month = nov,

day = "1",

doi = "10.1016/j.ijid.2014.06.021",

language = "English",

volume = "28",

pages = "74--9",

journal = "International Journal of Infectious Diseases",

issn = "1201-9712",

publisher = "Elsevier",

}

TY - JOUR

T1 - Campylobacter, Salmonella, and Yersinia antibodies and pregnancy outcome in Danish women with occupational exposure to animals

AU - Kantsø, Bjørn

AU - Andersen, Anne-Marie Nybo

AU - Mølbak, Kåre

AU - Krogfelt, Karen Angeliki

AU - Henriksen, Tine Brink

AU - Nielsen, Stine Yde

PY - 2014/11/1

Y1 - 2014/11/1

N2 - BACKGROUND: The aim of this study was to determine antibody titres against Campylobacter, Salmonella, and Yersinia in a population-based cohort of pregnant women in Denmark in order to evaluate adverse pregnancy outcomes (miscarriage, preterm birth, and small for gestational age) in relation to occupational exposure to animals in women exposed to food producing animals.METHODS: We used data and blood samples from the Danish National Birth Cohort. Serum samples collected during the first trimester from 192 pregnant women who were occupationally exposed to domestic animals and 188 randomly selected unexposed pregnant women were analysed for IgG, IgM, and IgA antibodies against Campylobacter, Salmonella, and Yersinia. Pregnancy outcomes of interest were identified through the Danish National Patient Register.RESULTS: Women with occupational exposure to animals had significantly higher IgG antibody concentrations against Campylobacter, Salmonella, and Yersinia, whereas they had lower concentrations of IgM and IgA antibodies.CONCLUSIONS: Serological markers were not identified as risk factors for adverse pregnancy outcomes, with the exception of elevated concentrations of Salmonella antibodies, which were found to be associated with an increased risk of preterm birth.

AB - BACKGROUND: The aim of this study was to determine antibody titres against Campylobacter, Salmonella, and Yersinia in a population-based cohort of pregnant women in Denmark in order to evaluate adverse pregnancy outcomes (miscarriage, preterm birth, and small for gestational age) in relation to occupational exposure to animals in women exposed to food producing animals.METHODS: We used data and blood samples from the Danish National Birth Cohort. Serum samples collected during the first trimester from 192 pregnant women who were occupationally exposed to domestic animals and 188 randomly selected unexposed pregnant women were analysed for IgG, IgM, and IgA antibodies against Campylobacter, Salmonella, and Yersinia. Pregnancy outcomes of interest were identified through the Danish National Patient Register.RESULTS: Women with occupational exposure to animals had significantly higher IgG antibody concentrations against Campylobacter, Salmonella, and Yersinia, whereas they had lower concentrations of IgM and IgA antibodies.CONCLUSIONS: Serological markers were not identified as risk factors for adverse pregnancy outcomes, with the exception of elevated concentrations of Salmonella antibodies, which were found to be associated with an increased risk of preterm birth.

U2 - 10.1016/j.ijid.2014.06.021

DO - 10.1016/j.ijid.2014.06.021

M3 - Journal article

C2 - 25245002

SN - 1201-9712

VL - 28

SP - 74

EP - 79

JO - International Journal of Infectious Diseases

JF - International Journal of Infectious Diseases

ER -

Campylobacter, Salmonella, and Yersinia antibodies and pregnancy outcome in Danish women with occupational exposure to animals

Abstract

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