Balancing benefit and risk of medicines: a systematic review and classification of available methodologies

Shahrul Mt-Isa, Christine E Hallgreen, Nan Wang, Torbjörn Callréus, Georgy Genov, Ian Hirsch, Stephen F Hobbiger, Kimberley S Hockley, Davide Luciani, Lawrence D Phillips, George Quartey, Sinan B Sarac, Isabelle Stoeckert, Ioanna Tzoulaki, Alain Micaleff, Deborah Ashby, IMI-PROTECT benefit-risk participants