Abstract
OBJECTIVES: Off-pump coronary surgery reduces transfusions, however, many patients still receive blood. This trial aims to clarify the effect of using a cell saver intraoperatively.
DESIGN: In 60 patients shed blood was collected in the cell saver reservoir intraoperatively; randomization and processing or discharge were performed immediately after surgery.
PRIMARY OUTCOME MEASURES: proportion of patients receiving allogeneic blood, and average number of units per patient.
SECONDARY OUTCOME MEASURES: blood loss, hemoglobin levels, complications, and costs.
RESULTS: Cell saver group versus control group; received transfusions: 17/30 vs. 14/29 (p = 0.28), allogeneic units: median 1 (interquartile range 0 - 2) vs. 2 (IQR 0 - 7) (p = 0.06), intraoperative net blood loss: median 300 ml (IQR 193 - 403) vs. 610 ml (IQR 450 - 928) (p < 0.001). Control group patients had more complications leading to transfusion. Hemoglobin levels and costs were comparable between groups.
CONCLUSIONS: Use of cell saver reduced intraoperative net blood loss and seemed to reduce transfusions by 1 unit per patient, however, this was probably attributable to more complications leading to transfusion in the control group. In the future larger trials are necessary.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Scandinavian Cardiovascular Journal |
| Vol/bind | 40 |
| Udgave nummer | 3 |
| Sider (fra-til) | 194-8 |
| Antal sider | 5 |
| ISSN | 1401-7431 |
| DOI | |
| Status | Udgivet - jun. 2006 |