Assessment of intersegmental coordination of rats during walking at different speeds - Application of continuous relative phase

TY - JOUR

T1 - Assessment of intersegmental coordination of rats during walking at different speeds - Application of continuous relative phase

AU - Raffalt, Peter Christian

AU - Nielsen, Louise R

AU - Madsen, Stefan

AU - Højberg, Laurits Munk

AU - Pingel, Jessica

AU - Nielsen, Jens Bo

AU - Alkjær, Tine

AU - Wienecke, Jacob

N1 - CURIS 2018 NEXS 129

PY - 2018/5/17

Y1 - 2018/5/17

N2 - The present study investigated the feasibility and reliability of continuous relative phase (CRP) and deviation phase (DP) to assess intersegmental hind limb coordination pattern and coordination variability in rats during walking. Twenty-six adult rats walked at 8 m/min, 12 m/min and 16 m/min while two-dimensional kinematics were recorded. Segment angles and segment angular velocities of the paw, shank and thigh on the left hind-limb were extracted from 15 strides and CRP was calculated for the paw-shank and shank-thigh coupling. The effect of walking speed on the time point average curve of the CRP (ACRP) and DP and on the mean ACRP and mean DP was established by statistical parametric mapping (SPM) and a one-way ANOVA for repeated measures. Absolute and relative reliability were assessed by measurement error and intra-class correlation coefficient. The SPM analysis revealed time dependent differences in the effect of speed. Thus, the CRP of the paw-shank coupling decreased with increasing speed during most of the gait cycle while the CRP of the shank-thigh coupling was decreased during the swing phase. The session-to-session reliability was fair to good for the coordination measure and poor for the variability measure.

AB - The present study investigated the feasibility and reliability of continuous relative phase (CRP) and deviation phase (DP) to assess intersegmental hind limb coordination pattern and coordination variability in rats during walking. Twenty-six adult rats walked at 8 m/min, 12 m/min and 16 m/min while two-dimensional kinematics were recorded. Segment angles and segment angular velocities of the paw, shank and thigh on the left hind-limb were extracted from 15 strides and CRP was calculated for the paw-shank and shank-thigh coupling. The effect of walking speed on the time point average curve of the CRP (ACRP) and DP and on the mean ACRP and mean DP was established by statistical parametric mapping (SPM) and a one-way ANOVA for repeated measures. Absolute and relative reliability were assessed by measurement error and intra-class correlation coefficient. The SPM analysis revealed time dependent differences in the effect of speed. Thus, the CRP of the paw-shank coupling decreased with increasing speed during most of the gait cycle while the CRP of the shank-thigh coupling was decreased during the swing phase. The session-to-session reliability was fair to good for the coordination measure and poor for the variability measure.

KW - Faculty of Science

KW - Coordination

KW - Locomotion

KW - Rodents

KW - Speed

U2 - 10.1016/j.jbiomech.2018.03.045

DO - 10.1016/j.jbiomech.2018.03.045

M3 - Journal article

C2 - 29650410

SN - 0021-9290

VL - 73

SP - 168

EP - 176

JO - Journal of Biomechanics

JF - Journal of Biomechanics

ER -