Arvelige hjertesygdomme forårsaget af natriumkanalmutationer

Jacob Tfelt-Hansen; Søren-Peter Olesen; Jesper Hastrup Svendsen; Thomas Jespersen

Arvelige hjertesygdomme forårsaget af natriumkanalmutationer

Jacob Tfelt-Hansen, Søren-Peter Olesen, Jesper Hastrup Svendsen, Thomas Jespersen

Physiology of circulation, kidney and lung

Abstract

Contraction of the heart is achieved through a delicately regulated conduction of electrical impulses. A pivotal element in the impulse propagation is the depolarising sodium current responsible for the initial depolarisation of the cardiomyocytes. Recent research has shown that mutations in the gene encoding the cardiac sodium channel (SCN5A) is associated with both rare forms of ventricular arrhythmia, and with the most frequent form of arrhythmia, atrial fibrillation.
Udgivelsesdato: 2009-Apr-6

Bidragets oversatte titel	Inherited cardiac diseases caused by Nav1.5 sodium channel mutations
Originalsprog	Dansk
Tidsskrift	Ugeskrift for læger
Vol/bind	171
Udgave nummer	15
Sider (fra-til)	1261-5
Antal sider	4
ISSN	0041-5782
Status	Udgivet - 2009

Citationsformater

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abstract = "Contraction of the heart is achieved through a delicately regulated conduction of electrical impulses. A pivotal element in the impulse propagation is the depolarising sodium current responsible for the initial depolarisation of the cardiomyocytes. Recent research has shown that mutations in the gene encoding the cardiac sodium channel (SCN5A) is associated with both rare forms of ventricular arrhythmia, and with the most frequent form of arrhythmia, atrial fibrillation. Udgivelsesdato: 2009-Apr-6",

author = "Jacob Tfelt-Hansen and S{\o}ren-Peter Olesen and Svendsen, {Jesper Hastrup} and Thomas Jespersen",

note = "Keywords: Atrial Fibrillation; Brugada Syndrome; Heart Conduction System; Humans; Long QT Syndrome; Muscle Proteins; Mutation; Sodium Channels",

year = "2009",

language = "Dansk",

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T1 - Arvelige hjertesygdomme forårsaget af natriumkanalmutationer

AU - Tfelt-Hansen, Jacob

AU - Olesen, Søren-Peter

AU - Svendsen, Jesper Hastrup

AU - Jespersen, Thomas

N1 - Keywords: Atrial Fibrillation; Brugada Syndrome; Heart Conduction System; Humans; Long QT Syndrome; Muscle Proteins; Mutation; Sodium Channels

PY - 2009

Y1 - 2009

N2 - Contraction of the heart is achieved through a delicately regulated conduction of electrical impulses. A pivotal element in the impulse propagation is the depolarising sodium current responsible for the initial depolarisation of the cardiomyocytes. Recent research has shown that mutations in the gene encoding the cardiac sodium channel (SCN5A) is associated with both rare forms of ventricular arrhythmia, and with the most frequent form of arrhythmia, atrial fibrillation. Udgivelsesdato: 2009-Apr-6

AB - Contraction of the heart is achieved through a delicately regulated conduction of electrical impulses. A pivotal element in the impulse propagation is the depolarising sodium current responsible for the initial depolarisation of the cardiomyocytes. Recent research has shown that mutations in the gene encoding the cardiac sodium channel (SCN5A) is associated with both rare forms of ventricular arrhythmia, and with the most frequent form of arrhythmia, atrial fibrillation. Udgivelsesdato: 2009-Apr-6

M3 - Tidsskriftartikel

C2 - 19416615

SN - 0041-5782

VL - 171

SP - 1261

EP - 1265

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 15

ER -