TY - CHAP
T1 - Aquaporins in the Eye
AU - Tran, Thuy Linh
AU - Hamann, Steffen
AU - Heegaard, Steffen
PY - 2017
Y1 - 2017
N2 - The major part of the eye consists of water . Continuous movement of water and ions between the ocular compartments and to the systemic circulation is pivotal for many physiological functions in the eye. The movement of water facilitates removal of the many metabolic products of corneal-, ciliary body-, lens- and retinal metabolism, while maintaining transparency in the optical compartments. Transport across the corneal epithelium and endothelium maintains the corneal transparency. Also, aqueous humour is continuously secreted by the epithelia of the ciliary body and maintains the intraocular pressure. In the retina, water is transported into the vitreous body and across the retinal pigment epithelium to regulate the extracellular environment and the hydration of the retina. Aquaporins (AQPs ) take part in the water transport throughout the eye.
AB - The major part of the eye consists of water . Continuous movement of water and ions between the ocular compartments and to the systemic circulation is pivotal for many physiological functions in the eye. The movement of water facilitates removal of the many metabolic products of corneal-, ciliary body-, lens- and retinal metabolism, while maintaining transparency in the optical compartments. Transport across the corneal epithelium and endothelium maintains the corneal transparency. Also, aqueous humour is continuously secreted by the epithelia of the ciliary body and maintains the intraocular pressure. In the retina, water is transported into the vitreous body and across the retinal pigment epithelium to regulate the extracellular environment and the hydration of the retina. Aquaporins (AQPs ) take part in the water transport throughout the eye.
KW - Animals
KW - Aquaporin 1/genetics
KW - Aqueous Humor/metabolism
KW - Biological Transport
KW - Cornea/cytology
KW - Diabetes Mellitus/genetics
KW - Gene Expression Regulation
KW - Humans
KW - Intraocular Pressure
KW - Lens, Crystalline/cytology
KW - Macular Degeneration/genetics
KW - Potassium Channels, Inwardly Rectifying/genetics
KW - Protein Isoforms/genetics
KW - Retinal Pigment Epithelium/cytology
KW - Vitreous Body/metabolism
KW - Water/metabolism
KW - Water-Electrolyte Balance
U2 - 10.1007/978-94-024-1057-0_12
DO - 10.1007/978-94-024-1057-0_12
M3 - Book chapter
C2 - 28258574
VL - 969
T3 - Advances in Experimental Medicine and Biology
SP - 193
EP - 198
BT - Aquaporins
A2 - Yang, Baoxue
ER -
