TY - JOUR
T1 - Apparent in vivo retroconversion of dietary arachidonic to linoleic acid in essential fatty acid-deficient rats
AU - Hansen, Harald S.
AU - Jensen, B.
AU - von Wettstein-Knowles, P.
PY - 1986/1/1
Y1 - 1986/1/1
N2 - Essential fatty acid-deficient rats were fed ethyl [U-C]arachidonate (308 dpm/nmol) and when a decrease in the transepidermal water loss was seen, the epidermal sphingolipids, acylglucosylceramide and acylceramide were isolated. [C]Linoleic acid (approx. 130 dpm/nmol) was present in both lipid classes, while the substrate was only detected in the former. These results intimate that in vivo retroconversion of arachidonic to linoleic acid can be induced in the rat.
AB - Essential fatty acid-deficient rats were fed ethyl [U-C]arachidonate (308 dpm/nmol) and when a decrease in the transepidermal water loss was seen, the epidermal sphingolipids, acylglucosylceramide and acylceramide were isolated. [C]Linoleic acid (approx. 130 dpm/nmol) was present in both lipid classes, while the substrate was only detected in the former. These results intimate that in vivo retroconversion of arachidonic to linoleic acid can be induced in the rat.
UR - http://www.scopus.com/inward/record.url?scp=0022475646&partnerID=8YFLogxK
M3 - Journal article
AN - SCOPUS:0022475646
SN - 1388-1981
VL - 878
SP - 284
EP - 287
JO - B B A - Molecular and Cell Biology of Lipids
JF - B B A - Molecular and Cell Biology of Lipids
IS - 2
ER -