Antibiotic tolerance and resistance in biofilms.

Oana Ciofu; Tim Tolker-Nielsen

Antibiotic tolerance and resistance in biofilms.

LUKKET: Institut for Immunologi og Mikrobiologi

Abstract

One of the most important features of microbial biofilms is their tolerance to antimicrobial agents and components of the host immune system. The difficulty of treating biofilm infections with antibiotics is a major clinical problem. Although antibiotics may decrease the number of bacteria in biofilms, they will not completely eradicate the bacteria in vivo which may have important clinical consequences in form of relapses of the infection.

Originalsprog	Engelsk
Titel	Biofilm Infections
Redaktører	T. Bjarnsholt, C. Moser, P.Ø. Jensen, N. Høiby
Antal sider	16
Udgivelsessted	New York, USA
Forlag	Springer Publishing Company
Publikationsdato	2010
Sider	215-230
ISBN (Trykt)	978-1-4419-6083-2
Status	Udgivet - 2010

Citationsformater

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title = "Antibiotic tolerance and resistance in biofilms.",

abstract = "One of the most important features of microbial biofilms is their tolerance to antimicrobial agents and components of the host immune system. The difficulty of treating biofilm infections with antibiotics is a major clinical problem. Although antibiotics may decrease the number of bacteria in biofilms, they will not completely eradicate the bacteria in vivo which may have important clinical consequences in form of relapses of the infection.",

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T1 - Antibiotic tolerance and resistance in biofilms.

AU - Ciofu, Oana

AU - Tolker-Nielsen, Tim

PY - 2010

Y1 - 2010

N2 - One of the most important features of microbial biofilms is their tolerance to antimicrobial agents and components of the host immune system. The difficulty of treating biofilm infections with antibiotics is a major clinical problem. Although antibiotics may decrease the number of bacteria in biofilms, they will not completely eradicate the bacteria in vivo which may have important clinical consequences in form of relapses of the infection.

AB - One of the most important features of microbial biofilms is their tolerance to antimicrobial agents and components of the host immune system. The difficulty of treating biofilm infections with antibiotics is a major clinical problem. Although antibiotics may decrease the number of bacteria in biofilms, they will not completely eradicate the bacteria in vivo which may have important clinical consequences in form of relapses of the infection.

M3 - Book chapter

SN - 978-1-4419-6083-2

SP - 215

EP - 230

BT - Biofilm Infections

A2 - Bjarnsholt, T.

A2 - Moser, C.

A2 - Jensen, P.Ø.

A2 - Høiby, N.

PB - Springer Publishing Company

CY - New York, USA

ER -