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Antiarrhythmic effect of IKr activation in a cellular model of LQT3
Jonas Goldin Diness
, Rie Schultz Hansen, Jakob Dahl Nissen,
Thomas Jespersen
, Morten Grunnet
Physiology of circulation, kidney and lung
18
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Keyphrases
Action Potential
16%
Action Potential Duration
33%
Antiarrhythmic Effect
100%
Clamp Study
16%
Current Injection
16%
Dose Effect
16%
Early Afterdepolarization
16%
Gain-of-function mutation
16%
Guinea pig
16%
I Kr
100%
Myocytes
16%
Nav1.5
33%
NS3623
66%
Patch Clamp
16%
Polymorphic Ventricular Tachycardia
16%
Repolarization
33%
Sudden Cardiac Death
16%
Syncope
16%
Torsades Des Pointes
16%
Triangulation
16%
Voltage-gated Sodium Channel
16%
Pharmacology, Toxicology and Pharmaceutical Science
Polymorphic Ventricular Tachycardia
20%
Sea Anemone Toxin
20%
Voltage Gated Sodium Channel
20%