Ankyloserende spondylitis er associeret med øget kardiovaskulær morbiditet og mortalitet

TY - JOUR

T1 - Ankyloserende spondylitis er associeret med øget kardiovaskulær morbiditet og mortalitet

AU - Madsen, Ole Rintek

AU - Lindhardsen, Jesper

PY - 2011/5

Y1 - 2011/5

N2 - Ankylosing spondylitis is an inflammatory disorder primarily affecting the axial skeleton. The disease is associated with increased cardiovascular morbidity and mortality. Structural changes in the heart, and arteriosclerosis secondary to inflammation may be of importance. The role of traditional cardiovascular risk factors and of anti-inflammatory treatment is unclear. Tumor necrosis factor inhibitors seem to increase cholesterol levels. Evaluation of the cardiovascular risk in these patients should be considered. Cardiovascular risk factors should be managed according to ordinary guidelines.

AB - Ankylosing spondylitis is an inflammatory disorder primarily affecting the axial skeleton. The disease is associated with increased cardiovascular morbidity and mortality. Structural changes in the heart, and arteriosclerosis secondary to inflammation may be of importance. The role of traditional cardiovascular risk factors and of anti-inflammatory treatment is unclear. Tumor necrosis factor inhibitors seem to increase cholesterol levels. Evaluation of the cardiovascular risk in these patients should be considered. Cardiovascular risk factors should be managed according to ordinary guidelines.

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 173

SP - 1503

EP - 1507

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 21

ER -