Anesthesia and the risk of dementia in the elderly

Jacob Steinmetz; Lars Simon Rasmussen

doi:10.1016/j.lpm.2018.03.013

Anesthesia and the risk of dementia in the elderly

Jacob Steinmetz, Lars Simon Rasmussen

Institut for Klinisk Medicin

4 Citationer (Scopus)

Abstract

Cognitive complications are common after surgery in the elderly, and with an increased number of elderly patients undergoing surgery, a potential impact of anaesthesia and surgery on long term cognition, and especially dementia would be concerning. The question whether anaesthesia and surgery in itself induce structural changes in the brain and thereby cognitive deterioration, or reveal a preexisting cognitive impairment remains unresolved. Several studies show an increased risk of reversible cognitive impairment after surgery in the elderly, but the risk of inducing dementia remains speculative. Further studies are needed to elucidate this potential association. Meanwhile, elderly frail patients need to be closely followed including preoperative cognitive screening, since they are at increased risk of cognitive deterioration after surgery and discharge.

Originalsprog	Fransk
Tidsskrift	Presse Medicale
Vol/bind	47
Udgave nummer	4 Pt 2
Sider (fra-til)	e45-e51
ISSN	0755-4982
DOI	https://doi.org/10.1016/j.lpm.2018.03.013
Status	Udgivet - apr. 2018

Emneord

Age Factors
Aged
Aged, 80 and over
Aging/psychology
Anesthesia/adverse effects
Cognition Disorders/epidemiology
Dementia/chemically induced
Humans
Postoperative Complications/epidemiology
Risk Factors

Adgang til dokumentet

10.1016/j.lpm.2018.03.013

Citationsformater

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title = "Anesthesia and the risk of dementia in the elderly",

abstract = "Cognitive complications are common after surgery in the elderly, and with an increased number of elderly patients undergoing surgery, a potential impact of anaesthesia and surgery on long term cognition, and especially dementia would be concerning. The question whether anaesthesia and surgery in itself induce structural changes in the brain and thereby cognitive deterioration, or reveal a preexisting cognitive impairment remains unresolved. Several studies show an increased risk of reversible cognitive impairment after surgery in the elderly, but the risk of inducing dementia remains speculative. Further studies are needed to elucidate this potential association. Meanwhile, elderly frail patients need to be closely followed including preoperative cognitive screening, since they are at increased risk of cognitive deterioration after surgery and discharge.",

keywords = "Age Factors, Aged, Aged, 80 and over, Aging/psychology, Anesthesia/adverse effects, Cognition Disorders/epidemiology, Dementia/chemically induced, Humans, Postoperative Complications/epidemiology, Risk Factors",

author = "Jacob Steinmetz and Rasmussen, {Lars Simon}",

year = "2018",

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doi = "10.1016/j.lpm.2018.03.013",

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volume = "47",

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T1 - Anesthesia and the risk of dementia in the elderly

AU - Steinmetz, Jacob

AU - Rasmussen, Lars Simon

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N2 - Cognitive complications are common after surgery in the elderly, and with an increased number of elderly patients undergoing surgery, a potential impact of anaesthesia and surgery on long term cognition, and especially dementia would be concerning. The question whether anaesthesia and surgery in itself induce structural changes in the brain and thereby cognitive deterioration, or reveal a preexisting cognitive impairment remains unresolved. Several studies show an increased risk of reversible cognitive impairment after surgery in the elderly, but the risk of inducing dementia remains speculative. Further studies are needed to elucidate this potential association. Meanwhile, elderly frail patients need to be closely followed including preoperative cognitive screening, since they are at increased risk of cognitive deterioration after surgery and discharge.

AB - Cognitive complications are common after surgery in the elderly, and with an increased number of elderly patients undergoing surgery, a potential impact of anaesthesia and surgery on long term cognition, and especially dementia would be concerning. The question whether anaesthesia and surgery in itself induce structural changes in the brain and thereby cognitive deterioration, or reveal a preexisting cognitive impairment remains unresolved. Several studies show an increased risk of reversible cognitive impairment after surgery in the elderly, but the risk of inducing dementia remains speculative. Further studies are needed to elucidate this potential association. Meanwhile, elderly frail patients need to be closely followed including preoperative cognitive screening, since they are at increased risk of cognitive deterioration after surgery and discharge.

KW - Age Factors

KW - Aged

KW - Aged, 80 and over

KW - Aging/psychology

KW - Anesthesia/adverse effects

KW - Cognition Disorders/epidemiology

KW - Dementia/chemically induced

KW - Humans

KW - Postoperative Complications/epidemiology

KW - Risk Factors

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DO - 10.1016/j.lpm.2018.03.013

M3 - Review

C2 - 29661618

SN - 0755-4982

VL - 47

SP - e45-e51

JO - Presse Medicale

JF - Presse Medicale

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