TY - JOUR
T1 - Analysis of 49 autosomal SNPs in an Iraqi population
AU - Tomas Mas, Carmen
AU - Diez, Isabel E
AU - Moncada, Enrique
AU - Børsting, Claus
AU - Morling, Niels
N1 - Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
PY - 2013/1
Y1 - 2013/1
N2 - Forty-nine of the 52 autosomal single nucleotide polymorphisms (SNPs) in the SNPforID 52plex were typed in 101 unrelated Iraqis living in Denmark. No significant deviation from HWE was found in all but one of the 49 SNP systems and no significant pairwise linkage disequilibrium was observed for any SNP pair. When 18 worldwide populations were compared (including populations in Iraq, Turkey, Israel, Pakistan, India, China, Taiwan, Japan, Siberia, Algeria, Somalia, Uganda, Mozambique, Angola, Nigeria, Denmark, Portugal, Spain), a significant global F(ST) value was obtained. All but six F(ST) values were statistically significant when pairwise comparisons were performed between the 18 populations. The Iraqi population did not show significant difference from the population in Turkey and it grouped together with other Middle-Eastern populations when a multidimensional scaling plot was drawn based on the pairwise F(ST) values. The combined mean match probability and the typical paternity index for trios were 8.3×10(-20) and 259,000, respectively, for the Iraqi population.
AB - Forty-nine of the 52 autosomal single nucleotide polymorphisms (SNPs) in the SNPforID 52plex were typed in 101 unrelated Iraqis living in Denmark. No significant deviation from HWE was found in all but one of the 49 SNP systems and no significant pairwise linkage disequilibrium was observed for any SNP pair. When 18 worldwide populations were compared (including populations in Iraq, Turkey, Israel, Pakistan, India, China, Taiwan, Japan, Siberia, Algeria, Somalia, Uganda, Mozambique, Angola, Nigeria, Denmark, Portugal, Spain), a significant global F(ST) value was obtained. All but six F(ST) values were statistically significant when pairwise comparisons were performed between the 18 populations. The Iraqi population did not show significant difference from the population in Turkey and it grouped together with other Middle-Eastern populations when a multidimensional scaling plot was drawn based on the pairwise F(ST) values. The combined mean match probability and the typical paternity index for trios were 8.3×10(-20) and 259,000, respectively, for the Iraqi population.
U2 - 10.1016/j.fsigen.2012.05.004
DO - 10.1016/j.fsigen.2012.05.004
M3 - Letter
C2 - 22652411
SN - 1872-4973
VL - 7
SP - 198
EP - 199
JO - Forensic Science International: Genetics
JF - Forensic Science International: Genetics
IS - 1
ER -