Analgesic Treatment in Laparoscopic Gastric Bypass Surgery: a Systematic Review of Randomized Trials

TY - JOUR

T1 - Analgesic Treatment in Laparoscopic Gastric Bypass Surgery

T2 - a Systematic Review of Randomized Trials

AU - Andersen, Lars P H

AU - Werner, Mads U

AU - Rosenberg, Jacob

AU - Gögenur, Ismail

PY - 2014/3

Y1 - 2014/3

N2 - This review aimed to present an overview of the randomized controlled trials investigating analgesic regimens used in laparoscopic Roux-en-Y gastric bypass (LRYGB) surgery. Literature search was performed in PubMed and EMBASE databases in August 2013 in accordance to PRISMA guidelines. The literature search identified nine studies eligible for inclusion. The administration of nonsteroidal anti-inflammatory drugs, local anesthetics (intraperitoneally or subfascially/subcutaneously), transversus abdominis plane block, dexmedetomidine, and ketamine may improve analgesia compared to placebo/controls in LRYGB. None of the studies incorporated multimodal procedure-specific analgesic regimens. The Oxford quality scoring system scores indicated a generally limited methodological quality of the included studies. This review documents a need for high-quality, procedure-specific literature concerning analgesic treatment in LRYGB surgery.

AB - This review aimed to present an overview of the randomized controlled trials investigating analgesic regimens used in laparoscopic Roux-en-Y gastric bypass (LRYGB) surgery. Literature search was performed in PubMed and EMBASE databases in August 2013 in accordance to PRISMA guidelines. The literature search identified nine studies eligible for inclusion. The administration of nonsteroidal anti-inflammatory drugs, local anesthetics (intraperitoneally or subfascially/subcutaneously), transversus abdominis plane block, dexmedetomidine, and ketamine may improve analgesia compared to placebo/controls in LRYGB. None of the studies incorporated multimodal procedure-specific analgesic regimens. The Oxford quality scoring system scores indicated a generally limited methodological quality of the included studies. This review documents a need for high-quality, procedure-specific literature concerning analgesic treatment in LRYGB surgery.

KW - Analgesics

KW - Anesthetics, Local

KW - Female

KW - Gastric Bypass

KW - Humans

KW - Laparoscopy

KW - Male

KW - Nerve Block

KW - Obesity, Morbid

KW - Pain Measurement

KW - Pain, Postoperative

KW - Randomized Controlled Trials as Topic

KW - Treatment Outcome

U2 - 10.1007/s11695-013-1172-z

DO - 10.1007/s11695-013-1172-z

M3 - Journal article

C2 - 24415221

SN - 0960-8923

VL - 24

SP - 462

EP - 470

JO - Obesity Surgery

JF - Obesity Surgery

IS - 3

ER -