Anafylaktisk shock efter intradermal injektion af steroidpræparat

TY - JOUR

T1 - Anafylaktisk shock efter intradermal injektion af steroidpræparat

AU - Meyer, Martin Willy

AU - Zachariae, Claus

AU - Garvey, Lene Heise

PY - 2015/1/19

Y1 - 2015/1/19

N2 - Carboxymethylcellulose (CMC) is a derivative of cellulose found in many food products, pharmaceuticals and cosmetics. Allergy to CMC in parenteral corticosteroid preparations leading to anaphylaxis is rare, but has previously been reported. We report a case of a 52-year-old woman with prurigo nodularis of Hyde, who reacted with anaphylaxis after intradermal injection of Kenalog 40 mg/ml. Allergy testing showed a positive skin prick test for CMC and the patient was advised to avoid future parenteral exposure to CMC. This case highlights the need to examine excipients in severe cases of drug allergy.

AB - Carboxymethylcellulose (CMC) is a derivative of cellulose found in many food products, pharmaceuticals and cosmetics. Allergy to CMC in parenteral corticosteroid preparations leading to anaphylaxis is rare, but has previously been reported. We report a case of a 52-year-old woman with prurigo nodularis of Hyde, who reacted with anaphylaxis after intradermal injection of Kenalog 40 mg/ml. Allergy testing showed a positive skin prick test for CMC and the patient was advised to avoid future parenteral exposure to CMC. This case highlights the need to examine excipients in severe cases of drug allergy.

M3 - Tidsskriftartikel

C2 - 25613209

SN - 0041-5782

VL - 177

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

M1 - V10140532

ER -