An evidence-based analysis of the management of N0 neck in patients with cancer of the parotid gland

Jose Guilherme Vartanian; Joao Gonçalves Filho; Luiz Paulo Kowalski; Jatin P Shah; Carlos Suárez; Alessandra Rinaldo; Remco De Bree; Juan P Rodrigo; Marc Hamoir; Robert P Takes; Antti A Mäkitie; Peter Zbären; Simon Andreasen; Vincent Vander Poorten; Alvaro Sanabria; Henrik Hellquist; K Thomas Robbins; Carsten C Bödeker; Carl Silver; Alfio Ferlito

doi:10.1080/14737140.2019.1674143

An evidence-based analysis of the management of N0 neck in patients with cancer of the parotid gland

Jose Guilherme Vartanian, Joao Gonçalves Filho, Luiz Paulo Kowalski, Jatin P Shah, Carlos Suárez, Alessandra Rinaldo, Remco De Bree, Juan P Rodrigo, Marc Hamoir, Robert P Takes, Antti A Mäkitie, Peter Zbären, Simon Andreasen, Vincent Vander Poorten, Alvaro Sanabria, Henrik Hellquist, K Thomas Robbins, Carsten C Bödeker, Carl Silver, Alfio Ferlito

Sektion 01

5 Citationer (Scopus)

Abstract

Introduction: Management of clinically negative neck (cN0) in patients with parotid gland cancer is controversial. Treatment options can include observation, elective neck dissection or elective radiotherapy. Areas covered: We addressed the treatment options for cN0 patients with parotid gland cancer. A literature review was undertaken to determine the optimal management of this group of patients. Expert opinion: Patients with parotid carcinoma and clinically negative neck have various options for their management. The analysis of tumor stage, histology and grade is essential to better define patients at risk for occult lymph node metastasis. These patients can be managed by surgery, radiotherapy or their combination, depending on the presence of risk factors, the moment at which such risk factors are detected, patient-related clinical conditions, medical provider expertise and institutional facilities.

Originalsprog	Engelsk
Tidsskrift	Expert Review of Anticancer Therapy
Sider (fra-til)	1-10
Antal sider	10
ISSN	1473-7140
DOI	https://doi.org/10.1080/14737140.2019.1674143
Status	E-pub ahead of print - 8 okt. 2019

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10.1080/14737140.2019.1674143

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Vartanian, J. G., Gonçalves Filho, J., Kowalski, L. P., Shah, J. P., Suárez, C., Rinaldo, A., De Bree, R., Rodrigo, J. P., Hamoir, M., Takes, R. P., Mäkitie, A. A., Zbären, P., Andreasen, S., Poorten, V. V., Sanabria, A., Hellquist, H., Robbins, K. T., Bödeker, C. C., Silver, C., & Ferlito, A. (2019). An evidence-based analysis of the management of N0 neck in patients with cancer of the parotid gland. Expert Review of Anticancer Therapy, 1-10. Advance online publication. https://doi.org/10.1080/14737140.2019.1674143

Vartanian, JG, Gonçalves Filho, J, Kowalski, LP, Shah, JP, Suárez, C, Rinaldo, A, De Bree, R, Rodrigo, JP, Hamoir, M, Takes, RP, Mäkitie, AA, Zbären, P, Andreasen, S, Poorten, VV, Sanabria, A, Hellquist, H, Robbins, KT, Bödeker, CC, Silver, C & Ferlito, A 2019, 'An evidence-based analysis of the management of N0 neck in patients with cancer of the parotid gland', Expert Review of Anticancer Therapy, s. 1-10. https://doi.org/10.1080/14737140.2019.1674143

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title = "An evidence-based analysis of the management of N0 neck in patients with cancer of the parotid gland",

abstract = "Introduction: Management of clinically negative neck (cN0) in patients with parotid gland cancer is controversial. Treatment options can include observation, elective neck dissection or elective radiotherapy. Areas covered: We addressed the treatment options for cN0 patients with parotid gland cancer. A literature review was undertaken to determine the optimal management of this group of patients. Expert opinion: Patients with parotid carcinoma and clinically negative neck have various options for their management. The analysis of tumor stage, histology and grade is essential to better define patients at risk for occult lymph node metastasis. These patients can be managed by surgery, radiotherapy or their combination, depending on the presence of risk factors, the moment at which such risk factors are detected, patient-related clinical conditions, medical provider expertise and institutional facilities.",

author = "Vartanian, {Jose Guilherme} and {Gon{\c c}alves Filho}, Joao and Kowalski, {Luiz Paulo} and Shah, {Jatin P} and Carlos Su{\'a}rez and Alessandra Rinaldo and {De Bree}, Remco and Rodrigo, {Juan P} and Marc Hamoir and Takes, {Robert P} and M{\"a}kitie, {Antti A} and Peter Zb{\"a}ren and Simon Andreasen and Poorten, {Vincent Vander} and Alvaro Sanabria and Henrik Hellquist and Robbins, {K Thomas} and B{\"o}deker, {Carsten C} and Carl Silver and Alfio Ferlito",

year = "2019",

month = oct,

day = "8",

doi = "10.1080/14737140.2019.1674143",

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journal = "Expert Review of Anticancer Therapy",

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T1 - An evidence-based analysis of the management of N0 neck in patients with cancer of the parotid gland

AU - Vartanian, Jose Guilherme

AU - Gonçalves Filho, Joao

AU - Kowalski, Luiz Paulo

AU - Shah, Jatin P

AU - Suárez, Carlos

AU - Rinaldo, Alessandra

AU - De Bree, Remco

AU - Rodrigo, Juan P

AU - Hamoir, Marc

AU - Takes, Robert P

AU - Mäkitie, Antti A

AU - Zbären, Peter

AU - Andreasen, Simon

AU - Poorten, Vincent Vander

AU - Sanabria, Alvaro

AU - Hellquist, Henrik

AU - Robbins, K Thomas

AU - Bödeker, Carsten C

AU - Silver, Carl

AU - Ferlito, Alfio

PY - 2019/10/8

Y1 - 2019/10/8

N2 - Introduction: Management of clinically negative neck (cN0) in patients with parotid gland cancer is controversial. Treatment options can include observation, elective neck dissection or elective radiotherapy. Areas covered: We addressed the treatment options for cN0 patients with parotid gland cancer. A literature review was undertaken to determine the optimal management of this group of patients. Expert opinion: Patients with parotid carcinoma and clinically negative neck have various options for their management. The analysis of tumor stage, histology and grade is essential to better define patients at risk for occult lymph node metastasis. These patients can be managed by surgery, radiotherapy or their combination, depending on the presence of risk factors, the moment at which such risk factors are detected, patient-related clinical conditions, medical provider expertise and institutional facilities.

AB - Introduction: Management of clinically negative neck (cN0) in patients with parotid gland cancer is controversial. Treatment options can include observation, elective neck dissection or elective radiotherapy. Areas covered: We addressed the treatment options for cN0 patients with parotid gland cancer. A literature review was undertaken to determine the optimal management of this group of patients. Expert opinion: Patients with parotid carcinoma and clinically negative neck have various options for their management. The analysis of tumor stage, histology and grade is essential to better define patients at risk for occult lymph node metastasis. These patients can be managed by surgery, radiotherapy or their combination, depending on the presence of risk factors, the moment at which such risk factors are detected, patient-related clinical conditions, medical provider expertise and institutional facilities.

U2 - 10.1080/14737140.2019.1674143

DO - 10.1080/14737140.2019.1674143

M3 - Journal article

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SN - 1473-7140

SP - 1

EP - 10

JO - Expert Review of Anticancer Therapy

JF - Expert Review of Anticancer Therapy

ER -

An evidence-based analysis of the management of N0 neck in patients with cancer of the parotid gland

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