Amitriptyline versus placebo for major depression

Lars Vedel Kessing; Jens Otto Drachmann Bukh

Amitriptyline versus placebo for major depression

Lars Vedel Kessing, Jens Otto Drachmann Bukh

Abstract

A recent Cochrane review concluded that amitriptyline is an efficacious antidepressant drug, however associated with a number of side effects. The present paper discusses this finding in relation to studies on effects and side effects of SSRIs and dual-action drugs. It is concluded that there is some evidence for recommending treatment with tricyclic antidepressants (TCA) especially in patients who are hospitalized with severe depression and melancholic features. Further, nortriptylin is preferred due to its more favourable side effects profile.

Bidragets oversatte titel	Amitriptyline versus placebo for major depression.
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	175
Udgave nummer	34
Sider (fra-til)	1875-1877
Antal sider	3
ISSN	0041-5782
Status	Udgivet - 19 aug. 2013

Adgang til dokumentet

http://svemedplus.kib.ki.se/Default.aspx?Dok_ID=129846

Citationsformater

@article{3711d92aa19d4e6bb85ce047f4b3cf02,

title = "Amitriptyline versus placebo for major depression",

abstract = "A recent Cochrane review concluded that amitriptyline is an efficacious antidepressant drug, however associated with a number of side effects. The present paper discusses this finding in relation to studies on effects and side effects of SSRIs and dual-action drugs. It is concluded that there is some evidence for recommending treatment with tricyclic antidepressants (TCA) especially in patients who are hospitalized with severe depression and melancholic features. Further, nortriptylin is preferred due to its more favourable side effects profile.",

author = "Kessing, {Lars Vedel} and Bukh, {Jens Otto Drachmann}",

year = "2013",

month = aug,

day = "19",

language = "Dansk",

volume = "175",

pages = "1875--1877",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "34",

}

TY - JOUR

T1 - Amitriptyline versus placebo for major depression

AU - Kessing, Lars Vedel

AU - Bukh, Jens Otto Drachmann

PY - 2013/8/19

Y1 - 2013/8/19

N2 - A recent Cochrane review concluded that amitriptyline is an efficacious antidepressant drug, however associated with a number of side effects. The present paper discusses this finding in relation to studies on effects and side effects of SSRIs and dual-action drugs. It is concluded that there is some evidence for recommending treatment with tricyclic antidepressants (TCA) especially in patients who are hospitalized with severe depression and melancholic features. Further, nortriptylin is preferred due to its more favourable side effects profile.

AB - A recent Cochrane review concluded that amitriptyline is an efficacious antidepressant drug, however associated with a number of side effects. The present paper discusses this finding in relation to studies on effects and side effects of SSRIs and dual-action drugs. It is concluded that there is some evidence for recommending treatment with tricyclic antidepressants (TCA) especially in patients who are hospitalized with severe depression and melancholic features. Further, nortriptylin is preferred due to its more favourable side effects profile.

M3 - Tidsskriftartikel

C2 - 23952981

SN - 0041-5782

VL - 175

SP - 1875

EP - 1877

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 34

ER -

Amitriptyline versus placebo for major depression

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater