Akut dissemineret encefalomyelitis er en vigtig differentialdiagnose hos det akut påvirkede barn

Isa Amalie Olofsson; Liselotte Skov; Maria Jose Miranda

Akut dissemineret encefalomyelitis er en vigtig differentialdiagnose hos det akut påvirkede barn

Isa Amalie Olofsson, Liselotte Skov, Maria Jose Miranda

Institut for Klinisk Medicin

1 Citationer (Scopus)

Abstract

Acute disseminated encephalomyelitis (ADEM) is an immune-mediated inflammatory paediatric disorder of the central nervous system (CNS). ADEM primarily affects the white matter of the brain and spinal cord. The aetiology of ADEM is unknown, but the illness is often precipitated by an infection, less often by vaccination. ADEM is characterized by acute polyfocal CNS deficit, including encephalopathy. This can be seen on MRI as simultaneously occurring multifocal lesions. Empirical treatment with steroids or immunoglobulins is often used. The prognosis of ADEM is usually favourable. This article describes two Danish cases both demonstrating trait characteristics of ADEM as well as the importance of an MRI considering an ADEM diagnosis early in the course of the illness.

Bidragets oversatte titel	Acute disseminated encephalomyelitis is an important differential diagnosis in the acutely affected child
Originalsprog	Dansk
Artikelnummer	V10140549
Tidsskrift	Ugeskrift for Laeger
Vol/bind	177
Udgave nummer	29
Sider (fra-til)	2-3
ISSN	0041-5782
Status	Udgivet - 13 jul. 2015

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http://ugeskriftet.dk.ep.fjernadgang.kb.dk/videnskab/akut-dissemineret-encefalomyelitis-er-en-vigtig-differentialdiagnose-hos-det-akut

Citationsformater

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abstract = "Acute disseminated encephalomyelitis (ADEM) is an immune-mediated inflammatory paediatric disorder of the central nervous system (CNS). ADEM primarily affects the white matter of the brain and spinal cord. The aetiology of ADEM is unknown, but the illness is often precipitated by an infection, less often by vaccination. ADEM is characterized by acute polyfocal CNS deficit, including encephalopathy. This can be seen on MRI as simultaneously occurring multifocal lesions. Empirical treatment with steroids or immunoglobulins is often used. The prognosis of ADEM is usually favourable. This article describes two Danish cases both demonstrating trait characteristics of ADEM as well as the importance of an MRI considering an ADEM diagnosis early in the course of the illness.",

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AU - Miranda, Maria Jose

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N2 - Acute disseminated encephalomyelitis (ADEM) is an immune-mediated inflammatory paediatric disorder of the central nervous system (CNS). ADEM primarily affects the white matter of the brain and spinal cord. The aetiology of ADEM is unknown, but the illness is often precipitated by an infection, less often by vaccination. ADEM is characterized by acute polyfocal CNS deficit, including encephalopathy. This can be seen on MRI as simultaneously occurring multifocal lesions. Empirical treatment with steroids or immunoglobulins is often used. The prognosis of ADEM is usually favourable. This article describes two Danish cases both demonstrating trait characteristics of ADEM as well as the importance of an MRI considering an ADEM diagnosis early in the course of the illness.

AB - Acute disseminated encephalomyelitis (ADEM) is an immune-mediated inflammatory paediatric disorder of the central nervous system (CNS). ADEM primarily affects the white matter of the brain and spinal cord. The aetiology of ADEM is unknown, but the illness is often precipitated by an infection, less often by vaccination. ADEM is characterized by acute polyfocal CNS deficit, including encephalopathy. This can be seen on MRI as simultaneously occurring multifocal lesions. Empirical treatment with steroids or immunoglobulins is often used. The prognosis of ADEM is usually favourable. This article describes two Danish cases both demonstrating trait characteristics of ADEM as well as the importance of an MRI considering an ADEM diagnosis early in the course of the illness.

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Akut dissemineret encefalomyelitis er en vigtig differentialdiagnose hos det akut påvirkede barn

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