Adherence to preventive statin therapy according to socioeconomic position

TY - JOUR

T1 - Adherence to preventive statin therapy according to socioeconomic position

AU - Wallach-Kildemoes, Helle

AU - Andersen, Morten

AU - Diderichsen, Finn

AU - Lange, Theis

PY - 2013/8

Y1 - 2013/8

N2 - AIM: To explore whether long-term adherence to preventive statin therapy depends on socioeconomic position (SEP). METHODS: A cohort of individuals without established cardiovascular disease (CVD) or diabetes initiating preventive statin therapy during 2002-2005 was followed in the individual-level Danish registries for 4 years or until censoring events (death, emigration, CVD or diabetes). Only individuals aged 40-84 years for whom information was available on the SEP indicators, education and income were included (N = 76,038). Two different aspects of poor adherence were applied as outcome measures: (1) Proportion of days covered (PDC) with medication below 80 %, assuming a daily dose of one tablet (continuity); (2) Discontinuation defined as a gap between two consecutive prescriptions exceeding 365 days (persistence). Stratum-specific logistic regression analyses were applied to estimate the odds ratio (OR) for PDC

AB - AIM: To explore whether long-term adherence to preventive statin therapy depends on socioeconomic position (SEP). METHODS: A cohort of individuals without established cardiovascular disease (CVD) or diabetes initiating preventive statin therapy during 2002-2005 was followed in the individual-level Danish registries for 4 years or until censoring events (death, emigration, CVD or diabetes). Only individuals aged 40-84 years for whom information was available on the SEP indicators, education and income were included (N = 76,038). Two different aspects of poor adherence were applied as outcome measures: (1) Proportion of days covered (PDC) with medication below 80 %, assuming a daily dose of one tablet (continuity); (2) Discontinuation defined as a gap between two consecutive prescriptions exceeding 365 days (persistence). Stratum-specific logistic regression analyses were applied to estimate the odds ratio (OR) for PDC

U2 - 10.1007/s00228-013-1488-6

DO - 10.1007/s00228-013-1488-6

M3 - Journal article

C2 - 23588558

SN - 0031-6970

VL - 69

SP - 1553

EP - 1563

JO - European Journal of Clinical Pharmacology

JF - European Journal of Clinical Pharmacology

IS - 8

ER -