Adaptations with intermittent exercise training in post- and premenopausal women

Kåre Seidelin; Michael Permin Nyberg; Peter Bergmann Piil; Niklas Rye Jørgensen; Ylva Hellsten; Jens Bangsbo

doi:10.1249/MSS.0000000000001071

Adaptations with intermittent exercise training in post- and premenopausal women

Kåre Seidelin, Michael Permin Nyberg, Peter Bergmann Piil, Niklas Rye Jørgensen, Ylva Hellsten, Jens Bangsbo

August Krogh Sektionen for Human Fysiologi

16 Citationer (Scopus)

Abstract

Introduction The purposes of the present study was to examine the effect of intermittent exercise training on musculoskeletal and metabolic health in postmenopausal (PM) and premenopausal (PRM) women and, furthermore, to evaluate whether the adaptations can be maintained with a reduced training frequency. Methods Eighteen PM (51 ± 1 yr, mean ± SEM) and 12 PRM (48 ± 1 yr) women participated in floorball training approximately two times per week for 12 wk. In a subgroup (n = 9) of PM women (PM40), exercise training was performed for an additional 40 wk with a reduced training frequency of approximately one training session per week. Results In PM, the body fat percentage decreased (P < 0.05) and the total lean leg mass increased (P < 0.05) during the 12-wk training period, with no changes in PRM. In both PM and PRM, lean body mass and maximal oxygen uptake (V-O 2max) were higher, and Yo-Yo intermittent endurance test 1 (YYIET-1) performance was better (P < 0.05) after the 12-wk training period. Procollagen type 1 amino-terminal propeptide was higher (P < 0.05) in PM, and total leg bone mineral density (BMD) was higher (P < 0.05) in both PM and PRM after the 12-wk training period. In PM40, total lean leg mass, V-O 2max, YYIET-1 performance, level of procollagen type 1 amino-terminal propeptide, and total leg BMD were maintained, whereas whole-body BMD and glycated hemoglobin (HbA1c) were reduced (P < 0.05) and the expression of muscle glucose transporter type 4 was higher (P < 0.05). Conclusion Twelve weeks of intermittent exercise training increased BMD, intermittent exercise capacity, and V-O 2max in PM and PRM, with PM also having positive changes in body composition. Additional 40 wk of training with a reduced frequency was sufficient to preserve these physiological adaptations and also improve blood glucose regulation in PM.

Originalsprog	Engelsk
Tidsskrift	Medicine and Science in Sports and Exercise
Vol/bind	49
Udgave nummer	1
Sider (fra-til)	96-105
Antal sider	10
ISSN	0195-9131
DOI	https://doi.org/10.1249/MSS.0000000000001071
Status	Udgivet - 1 jan. 2017

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abstract = "Introduction The purposes of the present study was to examine the effect of intermittent exercise training on musculoskeletal and metabolic health in postmenopausal (PM) and premenopausal (PRM) women and, furthermore, to evaluate whether the adaptations can be maintained with a reduced training frequency. Methods Eighteen PM (51 ± 1 yr, mean ± SEM) and 12 PRM (48 ± 1 yr) women participated in floorball training approximately two times per week for 12 wk. In a subgroup (n = 9) of PM women (PM40), exercise training was performed for an additional 40 wk with a reduced training frequency of approximately one training session per week. Results In PM, the body fat percentage decreased (P < 0.05) and the total lean leg mass increased (P < 0.05) during the 12-wk training period, with no changes in PRM. In both PM and PRM, lean body mass and maximal oxygen uptake (V-O 2max) were higher, and Yo-Yo intermittent endurance test 1 (YYIET-1) performance was better (P < 0.05) after the 12-wk training period. Procollagen type 1 amino-terminal propeptide was higher (P < 0.05) in PM, and total leg bone mineral density (BMD) was higher (P < 0.05) in both PM and PRM after the 12-wk training period. In PM40, total lean leg mass, V-O 2max, YYIET-1 performance, level of procollagen type 1 amino-terminal propeptide, and total leg BMD were maintained, whereas whole-body BMD and glycated hemoglobin (HbA1c) were reduced (P < 0.05) and the expression of muscle glucose transporter type 4 was higher (P < 0.05). Conclusion Twelve weeks of intermittent exercise training increased BMD, intermittent exercise capacity, and V-O 2max in PM and PRM, with PM also having positive changes in body composition. Additional 40 wk of training with a reduced frequency was sufficient to preserve these physiological adaptations and also improve blood glucose regulation in PM.",

keywords = "Faculty of Science, Bone formation marker, BMD, HbA1c, GLUT-4, Body composition, Floorball, Menopause",

author = "K{\aa}re Seidelin and Nyberg, {Michael Permin} and Piil, {Peter Bergmann} and J{\o}rgensen, {Niklas Rye} and Ylva Hellsten and Jens Bangsbo",

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T1 - Adaptations with intermittent exercise training in post- and premenopausal women

AU - Seidelin, Kåre

AU - Nyberg, Michael Permin

AU - Piil, Peter Bergmann

AU - Jørgensen, Niklas Rye

AU - Hellsten, Ylva

AU - Bangsbo, Jens

N1 - CURIS 2017 NEXS 023

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Introduction The purposes of the present study was to examine the effect of intermittent exercise training on musculoskeletal and metabolic health in postmenopausal (PM) and premenopausal (PRM) women and, furthermore, to evaluate whether the adaptations can be maintained with a reduced training frequency. Methods Eighteen PM (51 ± 1 yr, mean ± SEM) and 12 PRM (48 ± 1 yr) women participated in floorball training approximately two times per week for 12 wk. In a subgroup (n = 9) of PM women (PM40), exercise training was performed for an additional 40 wk with a reduced training frequency of approximately one training session per week. Results In PM, the body fat percentage decreased (P < 0.05) and the total lean leg mass increased (P < 0.05) during the 12-wk training period, with no changes in PRM. In both PM and PRM, lean body mass and maximal oxygen uptake (V-O 2max) were higher, and Yo-Yo intermittent endurance test 1 (YYIET-1) performance was better (P < 0.05) after the 12-wk training period. Procollagen type 1 amino-terminal propeptide was higher (P < 0.05) in PM, and total leg bone mineral density (BMD) was higher (P < 0.05) in both PM and PRM after the 12-wk training period. In PM40, total lean leg mass, V-O 2max, YYIET-1 performance, level of procollagen type 1 amino-terminal propeptide, and total leg BMD were maintained, whereas whole-body BMD and glycated hemoglobin (HbA1c) were reduced (P < 0.05) and the expression of muscle glucose transporter type 4 was higher (P < 0.05). Conclusion Twelve weeks of intermittent exercise training increased BMD, intermittent exercise capacity, and V-O 2max in PM and PRM, with PM also having positive changes in body composition. Additional 40 wk of training with a reduced frequency was sufficient to preserve these physiological adaptations and also improve blood glucose regulation in PM.

AB - Introduction The purposes of the present study was to examine the effect of intermittent exercise training on musculoskeletal and metabolic health in postmenopausal (PM) and premenopausal (PRM) women and, furthermore, to evaluate whether the adaptations can be maintained with a reduced training frequency. Methods Eighteen PM (51 ± 1 yr, mean ± SEM) and 12 PRM (48 ± 1 yr) women participated in floorball training approximately two times per week for 12 wk. In a subgroup (n = 9) of PM women (PM40), exercise training was performed for an additional 40 wk with a reduced training frequency of approximately one training session per week. Results In PM, the body fat percentage decreased (P < 0.05) and the total lean leg mass increased (P < 0.05) during the 12-wk training period, with no changes in PRM. In both PM and PRM, lean body mass and maximal oxygen uptake (V-O 2max) were higher, and Yo-Yo intermittent endurance test 1 (YYIET-1) performance was better (P < 0.05) after the 12-wk training period. Procollagen type 1 amino-terminal propeptide was higher (P < 0.05) in PM, and total leg bone mineral density (BMD) was higher (P < 0.05) in both PM and PRM after the 12-wk training period. In PM40, total lean leg mass, V-O 2max, YYIET-1 performance, level of procollagen type 1 amino-terminal propeptide, and total leg BMD were maintained, whereas whole-body BMD and glycated hemoglobin (HbA1c) were reduced (P < 0.05) and the expression of muscle glucose transporter type 4 was higher (P < 0.05). Conclusion Twelve weeks of intermittent exercise training increased BMD, intermittent exercise capacity, and V-O 2max in PM and PRM, with PM also having positive changes in body composition. Additional 40 wk of training with a reduced frequency was sufficient to preserve these physiological adaptations and also improve blood glucose regulation in PM.

KW - Faculty of Science

KW - Bone formation marker

KW - BMD

KW - HbA1c

KW - GLUT-4

KW - Body composition

KW - Floorball

KW - Menopause

U2 - 10.1249/MSS.0000000000001071

DO - 10.1249/MSS.0000000000001071

M3 - Journal article

C2 - 27992397

SN - 0195-9131

VL - 49

SP - 96

EP - 105

JO - Medicine and Science in Sports and Exercise

JF - Medicine and Science in Sports and Exercise

IS - 1

ER -

Adaptations with intermittent exercise training in post- and premenopausal women

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