TY - JOUR
T1 - Acute neurological signs as the predominant clinical manifestation in four dogs with Angiostrongylus vasorum infections in Denmark
AU - Gredal, Hanne Birgit
AU - Willesen, Jakob
AU - Jensen, Henrik Michael Elvang
AU - Nielsen, Ole Lerberg
AU - Kristensen, Annemarie Thuri
AU - Koch, Jørgen
AU - Kirk, Rikke K.
AU - Pors, Susanne Elisabeth
AU - Skerritt, Geoff C.
AU - Berendt, Mette
PY - 2011/6/28
Y1 - 2011/6/28
N2 - Four dogs with acute neurological signs caused by haemorrhages in the central nervous system were diagnosed with Angiostrongylus vasorum infection as the underlying aetiology. Two dogs presented with brain lesions, one dog with spinal cord lesions and one with lesions in both the brain and spinal cord. Only one dog presented with concurrent signs of classical pulmonary angiostrongylosis (respiratory distress, cough), and only two dogs displayed overt clinical signs of haemorrhages. Results of coagulation assays were inconsistent. Neurological signs reflected the site of pathology and included seizures, various cranial nerve deficits, vestibular signs, proprioceptive deficits, ataxia and paraplegia. One dog died and three were euthanised due to lack of improvement despite medical treatment. This emphasises canine angiostrongylosis as a potential cause of fatal lesions of the central nervous system and the importance of including A. vasorum as a differential diagnosis in young dogs with acute neurological signs in Denmark.
AB - Four dogs with acute neurological signs caused by haemorrhages in the central nervous system were diagnosed with Angiostrongylus vasorum infection as the underlying aetiology. Two dogs presented with brain lesions, one dog with spinal cord lesions and one with lesions in both the brain and spinal cord. Only one dog presented with concurrent signs of classical pulmonary angiostrongylosis (respiratory distress, cough), and only two dogs displayed overt clinical signs of haemorrhages. Results of coagulation assays were inconsistent. Neurological signs reflected the site of pathology and included seizures, various cranial nerve deficits, vestibular signs, proprioceptive deficits, ataxia and paraplegia. One dog died and three were euthanised due to lack of improvement despite medical treatment. This emphasises canine angiostrongylosis as a potential cause of fatal lesions of the central nervous system and the importance of including A. vasorum as a differential diagnosis in young dogs with acute neurological signs in Denmark.
U2 - 10.1186/1751-0147-53-43
DO - 10.1186/1751-0147-53-43
M3 - Journal article
C2 - 21711538
SN - 0044-605X
VL - 53
JO - Acta Veterinaria Scandinavica (Online)
JF - Acta Veterinaria Scandinavica (Online)
IS - 43
ER -