Actomyosin organisation for adhesion, spreading, growth and movement in chick fibroblasts.

TY - JOUR

T1 - Actomyosin organisation for adhesion, spreading, growth and movement in chick fibroblasts.

AU - Couchman, J R

AU - Rees, D A

N1 - Keywords: Actomyosin; Animals; Antigens; Cell Adhesion; Cell Division; Cell Movement; Cells, Cultured; Chick Embryo; Cytoskeleton; Fibroblasts; Fluorescent Antibody Technique; Microscopy, Electron; Microscopy, Interference; Myocardium

PY - 1979

Y1 - 1979

N2 - Examination of the actomyosin structures and their relation to adhesion, movement and growth in the first fibroblasts migrating from chick heart explants shows striking differences with fibroblasts adapted to grow in culture. The latter have focal adhesions which seem to immobilize them for anchorage-dependent growth, rather than facilitate their movement. The fibroblasts specialized for movement from the explants, though equally well spread, make contact with substratum through extensive areas of relatively unspecialized membrane, have less well developed stress fibres and a low growth rate.

AB - Examination of the actomyosin structures and their relation to adhesion, movement and growth in the first fibroblasts migrating from chick heart explants shows striking differences with fibroblasts adapted to grow in culture. The latter have focal adhesions which seem to immobilize them for anchorage-dependent growth, rather than facilitate their movement. The fibroblasts specialized for movement from the explants, though equally well spread, make contact with substratum through extensive areas of relatively unspecialized membrane, have less well developed stress fibres and a low growth rate.

M3 - Journal article

C2 - 385152

SN - 0309-1651

VL - 3

SP - 431

EP - 439

JO - Cell Biology International Reports

JF - Cell Biology International Reports

IS - 5

ER -