A survey of Crimean-Congo haemorrhagic fever in livestock and ticks in Ardabil Province, Iran during 2004-2005

TY - JOUR

T1 - A survey of Crimean-Congo haemorrhagic fever in livestock and ticks in Ardabil Province, Iran during 2004-2005

AU - Telmadarraiy, Z

AU - Ghiasi, Seyed Mojtaba

AU - Moradi, Maryam

AU - Vatandoost, Hasan

AU - Eshraghian, Mohammad Reza

AU - Faghihi, Faezeh

AU - Zarei, Zabiollah

AU - Haeri, Ali

AU - Chinikar, Sadegh

PY - 2010

Y1 - 2010

N2 - Crimean-Congo haemorrhagic fever (CCHF) is a viral haemorrhagic fever caused by the CCHF virus. It is mainly transmitted to humans and animals by ticks. In recent y, large numbers of livestock have been transported across the border areas of Ardabil Province resulting in an outbreak of CCHF in the adjacent districts. A comprehensive study was carried out to assess the epidemiological aspects of the disease in this province. In the study area, 130 ticks were collected from randomly selected villages and classified into 9 species of hard tick and 2 species of soft tick. All ticks were analyzed for the presence of CCHF virus genome using gel-based and real-time reverse transcriptase polymerase chain reactions (RT-PCR). The results showed CCHF infection in almost 28% of ticks collectively. Also, of 56 livestock sera, around 39% were IgG-positive. The presence of anti-CCHF virus IgG antibodies and the CCHF virus genome in ticks points to a great hidden threat of an outbreak in these districts. Those in high-risk professions in this province should be informed and trained on the risk of CCHF with urgency.

AB - Crimean-Congo haemorrhagic fever (CCHF) is a viral haemorrhagic fever caused by the CCHF virus. It is mainly transmitted to humans and animals by ticks. In recent y, large numbers of livestock have been transported across the border areas of Ardabil Province resulting in an outbreak of CCHF in the adjacent districts. A comprehensive study was carried out to assess the epidemiological aspects of the disease in this province. In the study area, 130 ticks were collected from randomly selected villages and classified into 9 species of hard tick and 2 species of soft tick. All ticks were analyzed for the presence of CCHF virus genome using gel-based and real-time reverse transcriptase polymerase chain reactions (RT-PCR). The results showed CCHF infection in almost 28% of ticks collectively. Also, of 56 livestock sera, around 39% were IgG-positive. The presence of anti-CCHF virus IgG antibodies and the CCHF virus genome in ticks points to a great hidden threat of an outbreak in these districts. Those in high-risk professions in this province should be informed and trained on the risk of CCHF with urgency.

KW - Animals

KW - Animals, Domestic

KW - Antibodies, Viral

KW - Hemorrhagic Fever Virus, Crimean-Congo

KW - Hemorrhagic Fever, Crimean

KW - Humans

KW - Immunoglobulin G

KW - Iran

KW - Prevalence

KW - RNA, Viral

KW - Reverse Transcriptase Polymerase Chain Reaction

KW - Seroepidemiologic Studies

KW - Ticks

U2 - 10.3109/00365540903362501

DO - 10.3109/00365540903362501

M3 - Journal article

C2 - 19958240

SN - 0036-5548

VL - 42

SP - 137

EP - 141

JO - Scandinavian Journal of Infectious Diseases

JF - Scandinavian Journal of Infectious Diseases

IS - 2

ER -