A comparison of the Hodgkin-Huxley model and the soliton theory for the action potential in nerves

TY - JOUR

T1 - A comparison of the Hodgkin-Huxley model and the soliton theory for the action potential in nerves

AU - Appali, R.

AU - van Rienen, U.

AU - Heimburg, Thomas Rainer

PY - 2012

Y1 - 2012

N2 - We describe the origin and significance of electrical and mechanical observations on nerves. To this end, we compare two models for neural activity, which are the established Hodgkin-Huxley model and the more recent soliton theory, respectively. While the Hodgkin-Huxley model focuses particularly on the electrical aspects of the neural membranes, the soliton model is based on hydrodynamic and thermodynamic properties of the membrane, thus including changes in all thermodynamic variables.

AB - We describe the origin and significance of electrical and mechanical observations on nerves. To this end, we compare two models for neural activity, which are the established Hodgkin-Huxley model and the more recent soliton theory, respectively. While the Hodgkin-Huxley model focuses particularly on the electrical aspects of the neural membranes, the soliton model is based on hydrodynamic and thermodynamic properties of the membrane, thus including changes in all thermodynamic variables.

M3 - Journal article

SN - 1554-4516

VL - 16

SP - 275

EP - 299

JO - Advances in Planar Lipid Bilayers and Liposomes

JF - Advances in Planar Lipid Bilayers and Liposomes

ER -