TY - JOUR
T1 - A collaborative study of the EDNAP group regarding Y-chromosome binary polymorphism analysis
AU - Brion, María
AU - Dupuy, Berit M
AU - Heinrich, Marielle
AU - Hohoff, Carsten
AU - Hoste, Bernardette
AU - Ludes, Bertrand
AU - Mevag, Bente
AU - Morling, Niels
AU - Niederstätter, Harald
AU - Parson, Walther
AU - Sanchez Sanchez, Juan Jose
AU - Bender, Klaus
AU - Siebert, Nathalie
AU - Thacker, Catherine
AU - Vide, Conceiçao
AU - Carracedo, Angel
N1 - Keywords: Chromosomes, Human, Y; DNA Fingerprinting; Europe; Genetic Markers; Genetics, Population; Haplotypes; Humans; Male; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Reproducibility of Results
PY - 2005
Y1 - 2005
N2 - A collaborative study was carried out by the European DNA Profiling Group (EDNAP) in order to evaluate the performance of Y-chromosome binary polymorphism analysis in different European laboratories. Four blood samples were sent to the laboratories, to be analysed for 11 Y-chromosome single nucleotide polymorphisms (SNPs): SRY-1532, M40, M35, M213, M9, 92R7, M17, P25, M18, M153 and M167. All the labs were also asked to submit a population study including these markers. All participating laboratories reported the same results, indicating the reproducibility and robustness of Y-chromosome SNP typing. A total of 535 samples from six different European populations were also analysed. In Galicia (NW Spain) and Belgium, the most frequent haplogroup was R1b*(xR1b1,R1b3df). Haplogroup F*(xK) is one of the most frequent in Austria and Denmark, while the lowest frequency appear in Belgium. Haplogroup frequencies found in this collaborative study were compared with previously published European Y-chromosome haplogroup data.
AB - A collaborative study was carried out by the European DNA Profiling Group (EDNAP) in order to evaluate the performance of Y-chromosome binary polymorphism analysis in different European laboratories. Four blood samples were sent to the laboratories, to be analysed for 11 Y-chromosome single nucleotide polymorphisms (SNPs): SRY-1532, M40, M35, M213, M9, 92R7, M17, P25, M18, M153 and M167. All the labs were also asked to submit a population study including these markers. All participating laboratories reported the same results, indicating the reproducibility and robustness of Y-chromosome SNP typing. A total of 535 samples from six different European populations were also analysed. In Galicia (NW Spain) and Belgium, the most frequent haplogroup was R1b*(xR1b1,R1b3df). Haplogroup F*(xK) is one of the most frequent in Austria and Denmark, while the lowest frequency appear in Belgium. Haplogroup frequencies found in this collaborative study were compared with previously published European Y-chromosome haplogroup data.
U2 - 10.1016/j.forsciint.2005.06.002
DO - 10.1016/j.forsciint.2005.06.002
M3 - Journal article
C2 - 16024201
SN - 0379-0738
VL - 153
SP - 103
EP - 108
JO - Forensic Science International
JF - Forensic Science International
IS - 2-3
ER -