Intet billede af Per Skallerup

Per Skallerup

20052018

Publikationer pr. år

Personlig profil

Primære forskningsområder

My research program is focused on genetic determinants of infectious diseases in pigs.

Kort præsentation

My research program is focused on genetic determinants of infectious diseases in pigs.
My current project aims at deciphering the genetic components controlling Staphylococcus aureus infections in pigs.

In my PhD I worked with the genetic components of Ascaris suum (roundworm) infection. This parasite has a global distribution and may be found in both large-scale and rural pig production systems. There is evidence that gene variants determine whether pigs are susceptible to infection or resistant. We have identified a genetic marker (single nucleotide polymorphism) on chromosome 4 which is associated with the number of A. suum worms in the pig. By comparing pigs with varying levels of resistance to A. suum, we have revealed some interesting differences in gene expression in mesenteric lymph nodes.
A close relative to A. suum infects humans. According to recent estimates, a billion people, primarily in the tropics, are infected with this parasite. We expect that the immunological mechanisms responsible for the variation in susceptibility to A. suum will be similar in humans.

Ekspertise relateret til FN’s Verdensmål

I 2015 blev FN-landende enige om 17 Verdensmål til at standse fattigdom, beskytte planeten og sikre velstand for alle. Denne persons arbejde bidrager til følgende verdensmål:

  • Verdensmål 3 - Sundhed og trivsel

Emneord

  • Det Sundhedsvidenskabelige Fakultet
  • Vært-patogen relationer
  • Immunologi
  • Bioinformatik
  • Værtsgenetik
  • Parasitologi
  • Genekspression
  • Infektionssygdomme
  • Sygdomsbekæmpelse
  • Mikrobiologi

Fingeraftryk

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  • 7 Lignende profiler